Updating and Enriching an Undergraduate Physiology Laboratory Curriculum by Introducing Modern Techniques using an Inquiry-based Learning Model

生物科学（61）这个项目的目的是准备和激励学生走上成功的事业在尖端的科学研究或教学通过引入探究为基础的学习策略到生理学实验室课程。 教育学生如何做研究最好是通过让他们参与研究来完成。 在这个项目中，学生1）设想假设; 2）计划项目; 3）进行实验; 4）批判性地分析结果; 5）制定研究的下一步。 通过该项目在实验室引入的设备使学生接触到一系列当代技术和技能，以便在他们进行研究时，他们意识到在项目进展中引入的每种技术/设备的实用性。 当学生参与实验设计和发现的过程，而不是遵循提供给他们的协议时，他们对研究的兴趣得到了激发。 这种方法如下的NSF资助的项目在洛约拉学院的例子，其中学生使用“目标导向的方法，...在小组中合作回答基本的生物学问题。" 学生的调查比较了那些参加新的生理学实验室课程的职业道路相比，以前的学生的生理浓度。 我们正在更新和丰富我们的本科生理学实验室课程，通过介绍当前的研究设备和技术的研究项目的范围内。 我们计划通过扩大统一的主题和研究项目，整合最近建立的课程，细胞生理学和基因组学实验室，“研究细胞培养系统中凋亡基因的转染，表达和作用。“引入研究方向的方法也被纳入我们的动物生理学实验和组织学课程。 利用康奈尔大学教师的专业知识，这两门课程的学生都参与了对患有心肌病的转基因小鼠进行表型分析。 组织学的学生检查形态，而生理学的学生检查与正常心脏相比的修改的功能。 所购置的设备也可供参加“生物学本科研究”课程的学生使用，在该课程中，学生可以继续从事其他实验室课程开始的研究。

Biological Sciences (61) The aim of this project is to prepare and inspire students to embark on successful careers in cutting edge scientific research or teaching by introducing inquiry-based learning strategies into the physiology laboratory curriculum. Educating students in how to do research is best accomplished by engaging them in research. In this project students are 1) conceiving of hypotheses; 2) planning projects, 3) carrying out the experiments; 4) critically analyzing the results, and 5) formulating the next step in the research. The equipment being introduced in the laboratory through this project exposes students to an array of contemporary technologies and skills, so that as they pursue their research they become aware of the utility of each technique/equipment introduced in the progression of the project. The interest of students in research is stimulated when they participate in the process of experimental design and discovery rather than following protocols provided to them. This approach follows the example of an NSF funded project at Loyola College in which students used a "goal-oriented approach, ... working cooperatively in small groups to answer basic biological questions..." A survey of students compares the career paths of those participating in the new Physiology Laboratory curriculum as compared to previous students of the Physiology concentration. We are updating and enriching four of our Undergraduate Physiology Laboratory courses by introducing current research equipment and techniques within the context of a research project. We plan to integrate a recently established course, Cell Physiology and Genomics Laboratory, by expanding a unifying theme and research project, "Investigating the Transfection, Expression and Role of Apoptotic Genes in a Cell Culture System." The approach of introducing a research orientation is also being adopted into our courses in Animal Physiology Experimentation, and Histology. Taking advantage of faculty expertise at Cornell, students in both courses are involved in phenotyping genetically modified mice with cardiomyopathyies. Histology students examine the morphology while Physiology students examine the function of modified as compared to normal hearts. The equipment acquired is also accessible to students enrolled in "Undergraduate Research in Biology," a course in which students can continue to pursue research started in the other laboratory courses.