Acquisition of Instrumentation for Establishing a Microarray Core

在大卫林博士的指导下，康奈尔大学获得了一笔赠款，用于部分支持核心微阵列设施中使用的仪器。这些仪器包括标准微阵列平台、点样阵列平台、杂交站和液体处理器。该设施将被安置在康奈尔大学校园的兽医研究塔。同时监测数千个基因活动的能力，为不同的模型系统和问题带来了新的见解。此外，微阵列数据的解释可以鼓励跨学科的互动，促进计算机科学家，统计学家和生物学家之间的合作。微阵列使用的快速增长，加上各种基因组计划的完成，激发了人们对基因组学的兴趣。这反过来又吸引了越来越多的研究生和本科生到这个新的研究领域。这些仪器将补充校园现有的设备，使大量的教师完成广泛的微阵列实验。教师将能够：执行标准和点样阵列实验，创建定制库，打印定制芯片，杂交和扫描芯片，并使用可用的软件分析数据。康奈尔大学还在开发一个旨在培训研究生和本科生的基因组学研究计划。作为该计划的一个组成部分，该核心将使康奈尔大学成功地满足教师，博士后研究员，研究生和本科生的需求。这将改善跨部门单位科学家对最先进仪器的使用，并有望促进康奈尔大学校园不同成员之间的互动，包括生物学家，计算机科学家和统计学家。

A grant has been awarded to Cornell University under the direction of Dr. David Lin for partial support of instruments to be utilized in a core microarray facility. These instruments include a standard microarray platform, a spotted array platform, a hybridization station, and a liquid handler. The facility will be housed in the Veterinary Research Tower on the Cornell campus. The ability to monitor the activity of thousands of genes at once has generated new insight into diverse model systems and questions. In addition, the interpretation of microarray data can encourage interactions across disciplines, promoting collaborations among computer scientists, statisticians, and biologists. The rapid rise in microarray use, coupled with the completion of the various Genome Projects, has fueled interest in genomics. This in turn has attracted growing numbers of graduate and undergraduate students to this new field of study. These instruments will supplement existing equipment on campus, enabling a large number of faculty to complete a wide range of microarray experiments. Faculty will be able to: perform standard and spotted array experiments, create custom libraries, print custom chips, hybridize and scan chips, and use available software to analyze the data. Cornell is also developing a Genomics Program of Study aimed at training graduate and undergraduate students. As a component of this program, this Core will position Cornell to successfully provide for the needs of faculty, postdoctoral fellows, graduate students, and undergraduates. This will improve access to and increase the use of state-of-the-art instrumentation for research by scientists across departmental units and is expected to promote interactions among diverse members of the Cornell campus, including biologists, computer scientists and statisticians.