Conference: 3rd International Congress on Plant Metabolomics to be held June 2004 in Ames, Iowa

要求为2004年6月3日至6日在爱荷华州艾姆斯的爱荷华州立大学举行的第三届国际植物代谢学大会提供部分支持。会议将包括9位受邀演讲者的演讲，他们是植物代谢组学不同方面的领导者。最多12位发言者将从提交的简短口头报告摘要中挑选出来。会议还包括海报会议和非正式讨论的时间。会议结合了计划和教育的特点，以鼓励代表实验系统、职业水平、种族和性别多样性的科学家和学生有意义的参与。智力上的优点：自从第一个植物基因组(拟南芥)测序以来，已经有可能设想围绕植物的整个基因互补的功能。这一挑战体现了一种基于系统的方法来可视化整个基因组的表达。具体地说，已经开发了在mRNA(转录组)和蛋白质(蛋白质组学)水平上全球测量基因表达的技术。代谢组学是一种在代谢物水平上全球测量基因表达的技术，它可能代表了可以化学定义的基因组功能的最终表达。代谢组学是一个新兴的领域。国际植物代谢学大会是在两年前发起的，是将这一新兴植物功能基因组学领域的领先实践者聚集在一起的媒介。之前的会议都是在欧洲举行的，这次是本系列的第三次会议，将是第一次在美国举行。大会将首次在美国为植物生物学家、化学家和生物信息学家提供一个里程碑式的机会，让他们在关于植物代谢组学的重大国际会议的背景下会面、讨论和互动。这次研讨会将是爱荷华州立大学植物科学研究所正在举办的一系列研讨会之一。该计划将讨论代谢组学在基因发现和定向基因组修改中的当前和潜在应用。广泛影响：本次研讨会旨在启动和促进代谢组学从业者和研究植物生物学的研究人员之间的互动。演讲者被选中介绍关于各种相关主题的研究，包括新分析技术的开发、代谢组学数据的统计分析以及代谢组学在通过系统方法解决生物问题方面的作用。受邀发言者中约有三分之一是妇女；将从提交的摘要中再挑选至多12个简短的演讲，以增加职业一级的多样性，并加强代表不足群体的参与。这些研讨会的一个重要目的是促进研究人员之间的互动和新的合作，这些研究人员通常不会在一个研讨会上聚集在一起。除了研究生和博士后研究人员的参与外，还将特别努力鼓励NSF-REUS、其他本科生和感兴趣的高中教师参与。ISU与历史上的黑人机构和本科生研究经验项目的长期关系将培养代表不足的学生的出勤率。

Partial support is requested for the 3rd International Congress on Plant Metabolomics to be held from June 3 to 6, 2004 at Iowa State University, Ames, Iowa. The meeting will include presentations by 9 invited speakers who are leaders in different aspects of plant metabolomics. Up to twelve additional speakers will be selected from submitted abstracts for short oral presentations. The meeting also includes poster sessions and time for informal discussions. The conference incorporates programmatic and educational features to encourage meaningful participation by scientists and students representing diversity in experimental system, career level, ethnicity and gender.Intellectual Merit: Since the sequencing of the first plant genome (Arabidopsis), it has become possible to envision the functionality of the entire complement of genes that encompasses a plant. This challenge has manifested a systems-based approach to visualize the expression of the entire genome. Specifically, technologies for globally measuring gene expression at the mRNA (transcriptomics) and protein (proteomics) levels have been developed. Metabolomics is the technology for globally measuring gene expression at the metabolite level, which probably represents the ultimate expression of the functionality of a genome that can be chemically defined. Metabolomics is an emerging field. The International Congress on Plant Metabolomics was initiated just 2 years ago and is the medium that brings together the leading practitioners in this new emerging area of plant functional genomics. Previous meetings have been held in Europe, and this, 3rd meeting in this series will be the first to be held in the US. The Congress will for the first time in this country provide a landmark opportunity for plant biologists, chemists and bioinformaticists to meet, discuss and interact in the context of a major international meeting on plant metabolomics. The Symposium will be one of an ongoing series of symposia sponsored by the Plant Sciences Institute at Iowa State University. The program will address the current and potential applications of metabolomics in gene discovery and directed genome modifications.Broader Impacts: This symposium is designed to initiate and foster interactions among practitioners of metabolomics and researchers studying plant biology. The speakers have been chosen to present investigations on a variety of related topics, including the development of new analytical technologies, statistical analysis of metabolomics data, and the role of metabolomics in solving biological problems via a systems approach. Approximately one third of the invited speakers are women; up to twelve additional short talks will be selected from submitted abstracts to increase diversity in career level and to enhance participation of underrepresented groups. An important purpose of these symposia is to promote interactions and new collaborations among researchers who might not normally come together at a single symposium. In addition to the attendance of graduate students and post-doctoral researchers, special efforts will be made to encourage participation by NSF-REUs, other undergraduate students, and interested high school teachers. Long-standing relationships of ISU with historically black institutions and undergraduate research experience programs will foster attendance of underrepresented students.