SGER: Organometallic-inorganic hybrid catalysts for olefin metathesis: sol-gel synthesis in supercritical carbon dioxide

摘要提案标题：SGER：烯烃复分解有机金属-无机杂化催化剂：超临界二氧化碳中的溶胶-凝胶合成建议编号：CTS-0444356主要研究者：H。亨利兰姆机构： 北卡罗来纳州该提案的目的是设计和合成在二氧化硅气凝胶基质内结合准分子有机过渡金属络合物的固体催化剂。 四烷氧基硅烷与溶胶-凝胶官能化的有机金属前体的共缩合将在超临界二氧化碳中进行。 要探索的具体课题包括：控制的核和3-D空间结构的活性位点，键合的金属中心的气凝胶框架，和疏水性/亲水性的气凝胶孔。 广泛的强大的光谱技术将用于表征催化剂，包括NMR，XAFS和DRIFTS。 将检查催化剂在末端、内部和官能化烯烃的复分解中的活性和选择性。 烯烃复分解在精细化学品和药物的合成中具有重要的应用，并且存在与生物可再生物的转化相关的新机会。 该项目将为一名女研究生提供极好的教育经历。 将通过期刊出版物和在国家会议上介绍的方式传播研究结果。 定向功能的能力将是一个重大的进步，并可能改变这一领域的合成催化化学。 首席研究员选择了一个重要的催化转化进行研究，如果该项目最终证明成功，潜在的工业应用可能会迅速增长。

AbstractProposal Title: SGER: Organometallic-Inorganic Hybrid Catalysts for Olefin Metathesis: Sol-Gel Synthesis in Supercritical Carbon Dioxide Proposal Number: CTS-0444356Principal Investigators: H. Henry LambInstitution: North Carolina State The objective of this proposal is to design and synthesize solid catalysts incorporating quasi-molecular organo-transition metal complexes within a silica aerogel matrix. Co-condensation of tetraalkoxysilanes with sol-gel functionalized organometallic precursors will be performed in supercritical carbon dioxide. Specific topics to be explored include: control of the nuclearity and 3-D spatial configuration of the active sites, bonding of the metal centers to the aerogel framework, and hydrophobicity/hydrophilicity of the aerogel pores. A broad range of powerful spectroscopic techniques will be used to characterize the catalysts, including NMR, XAFS, and DRIFTS. The catalysts will be examined for activity and selectivity in the metathesis of terminal, internal, and functionalized olefins. Olefin metathesis has important applications in the synthesis of fine chemicals and pharmaceuticals, and there are new opportunities related to the conversion of biorenewables. The project will provide an excellent educational experience for a female graduate student. Dissemination of the results will be through journal publications and presentations at national meetings. The ability to orient functionality will be a major advance and could transform this area of synthetic catalytic chemistry. The principal investigator has chosen an important catalytic conversion to examine, and the potential industrial applications could grow rapidly if the project proves ultimately successful.