Selective Activation of Carbon-Fluorine Bonds Using Transition Metal Complexes

罗素·休斯教授是达特茅斯学院化学系的一名教员，他得到了无机、生物无机和有机金属化学项目的支持，开发了用过渡金属试剂激活通常惰性碳氟键的方法。将碳氟键转化为碳氢键或碳碳键是这个项目的目标之一。挥发性氟碳衍生物对大气化学的影响是巨大的，打破强C-F单键的能力是本研究项目的重要组成部分。取代氯氟烃化学品作为制冷剂和清洁溶剂是二十一世纪的一个重要目标。氢氟碳化合物是一种有吸引力的替代品，与氯化类似物相比具有良好的性能，为了充分利用这些化学品的潜在用途，必须开发碳氟键的化学转化。在与全球变暖有关的化学领域对学生进行培训，为将来规划环境影响方面的考虑提供了更充分的准备。

Professor Russell Hughes, a faculty member in the Department of Chemistry at Dartmouth College, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program to develop methods for activating normally inert carbon-fluorine bonds with transition metal reagents. The conversion of C-F bonds to either C-H or C-C bonds is one goal of this project. The impact of volatile fluorocarbon derivatives on atmospheric chemistry is substantial, and the ability to break strong C-F single bonds is an important component of this research project. Replacement of chlorofluorocarbon chemicals as refrigerants and cleaning solvents is an important goal for the twenty-first century. Hydrofluorocarbons are an attractive alternative with favorable properties relative to the chlorinated analogs, and development of chemical transformations of carbon fluorine bonds is necessary to capitalize on the potential use of these chemicals. Training students in areas of chemistry relevant to global warming provides a work force that is better prepared for future planning with respect to environmental impact considerations.