SGER: Ecotoxicological and functional genomic responses of Killifish in the aftermath of Hurricane Katrina
SGER: Ecotoxicological and functional genomic responses of Killifish in the aftermath of Hurricane Katrina
批准号:
0553523
负责人:
Andrew Whitehead
金额:
$2.99万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-10-15 至 2006-09-30
中文摘要
0553523 Whitehead这项研究的总体目标是评估卡特里娜飓风落尘对沼泽鱼类健康的影响,并测试环境化学物质浓度是否可预测功能基因组反应,以及功能基因组反应是否可预测生理反应。这将通过将功能基因组工具与应激和毒性的生理措施相结合,并通过将实地收集的观察结果与受控实验室实验相结合来实现。生物数据最终将与分析化学相结合,以测试与卡特里娜飓风后果相关的化学物质浓度是否可预测生物反应,并检查庞恰特雷恩湖生态系统恢复的时间进程
英文摘要
0553523 Whitehead The overarching goal of this proposed research is to evaluate the effects of Hurricane Katrina fallout on the health of marsh fishes, and to test whether environmental chemical concentrations are predictive of functional genomic responses and whether functional genomic responses are predictive of physiological responses. This will be achieved by coupling functional genomic tools with physiological measures of stress and toxicity, and by integrating observations collected in the field with controlled laboratory experiments. Biological data will eventually be coupled with analytical chemistry to test whether concentrations of chemicals associated with the aftermath of Hurricane Katrina are predictive of biological responses, and to examine the timecourse of recovery in the Lake Ponchatrain ecosystem
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海外基金