Experiments using Force-Detected Nuclear Magnetism: Coherent Electrons, Soft Matter, and Nanoscale NMR
Experiments using Force-Detected Nuclear Magnetism: Coherent Electrons, Soft Matter, and Nanoscale NMR
批准号:
0605828
负责人:
John Markert
金额:
$33.0万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-08-01 至 2011-07-31
中文摘要
非技术摘要:该研究项目将磁共振成像(MRI)技术扩展到更高的微观分辨率,目前MRI的分辨率仅为毫米(例如,在人脑的医学成像中)。因此,该项目将能够对单个生物细胞进行MRI成像,以绘制出结构和功能,例如识别癌细胞。此外,磁共振显微镜技术将用于研究电子材料;例如,用于识别目前阻碍微芯片进一步小型化的半导体缺陷。这项研究的一个最终目标是发展对单个原子级磁体成像的能力;这样一个宝贵的成就将使生物分子的结构识别(例如,用于反生物恐怖主义的努力和合理设计药物和疫苗),以及为所谓的"量子计算机"提供一个模型系统,该系统已被提议作为一种强大的密码工具,影响安全和商业。该项目还将大大扩大我们在纳米科学和纳米技术方面的教育努力,为本科生和研究生提供研究培训,包括德克萨斯大学奥斯汀分校的女学生和少数民族学生,并建立一个新的高能力科学家库。这项工作还将为我们的UTeach物理教育硕士项目的学生提供研究项目,该项目已被证明可以培养和留住更多高素质的高中科学教师。技术摘要:该研究项目将使用力检测核磁共振的新技术来进行几种类型的材料研究,探测微观尺度的属性,包括电子材料的激发和软物质的动力学。该技术结合了磁共振和扫描探针显微镜,将核磁耦合到安装在机械微振荡器上的微磁体。电子材料的研究将探索金属-绝缘体和金属-超导体转变的各向异性,在几种化合物中,只有微米尺寸的单晶存在。软物质研究将探测单个生物分子的结构,功能和扩散研究。此外,该研究将进一步发展单核自旋探测,提供20纳米分辨率的可行性研究,并获得有关单自旋探测所需的反馈,稳定和纳米磁体技术的信息。单自旋探测的目标包括成像应用和核自旋态的相干耦合和受控纠缠,后者为量子计算提供模型固态系统。 成像应用包括单个生物分子的成像和电子器件的表面下成像。该项目将大大扩大我们在纳米科学和纳米技术方面的教育努力,为本科生和研究生提供研究培训,包括德克萨斯大学奥斯汀分校的女性和少数民族学生,并建立一个新的高能力科学家库。这项工作还将为我们的UTeach物理教育硕士项目的学生提供研究项目,该项目已被证明可以培养和留住更多高素质的高中科学教师。
英文摘要
Non-Technical Abstract:The research project extends the technique of magnetic resonance imaging (MRI), which now has only millimeter resolution (for example, in medical imaging of the human brain), to much higher, microscopic resolution. Thus the project will enable MRI imaging of single biological cells, to map out structure and function, and, for example, to identify cancerous cells. In addition, the magnetic resonance microscopy technique will be used to study electronic materials; for example, to identify defects in semiconductors that are currently preventing further miniaturization of microchips. One ultimate goal of this research is to develop the ability to image single, atom-scale magnets; such an invaluable achievement would enable the identification of the structure of biological molecules (for example, for anti-bioterrorism efforts and for the rational design of drugs and vaccines), as well as provide a model system for a so-called "quantum computer" which has been proposed as a powerful cryptography tool, impacting security and commerce. The project will also greatly expand our educational efforts in nanoscience and nanotechnology, providing research training of undergraduate and graduate students, including female and minority students at the University of Texas at Austin, and establishing a new pool of highly capable scientists. The effort will also provide research projects for students in our UTeach Master's in Physics Education program, which has been proven to produce and retain more highly qualified high school science teachers.Technical Abstract:The research project will use the new technology of force-detected nuclear magnetic resonance to perform several types of materials studies, probing micro-scale properties, including excitations in electronic materials and dynamics in soft matter. The technology combines magnetic resonance with scanning-probe microscopy, coupling the nuclear magnetism to micromagnets mounted on mechanical micro-oscillators. The electronic materials studies will probe the anisotropy of metal-insulator and metal-superconductor transitions in several compounds for which only micron-sized single crystals exist. The soft-matter studies will probe single biological molecules for structure, function, and diffusion studies. In addition, the research will further the development of single-nuclear-spin detection, providing a feasibility study with 20-nanometer resolution, and obtaining information on the feedback, stabilization, and nanomagnet technologies required for single-spin detection. The goals of single-spin detection include imaging applications and the coherent coupling and controlled entanglement of nuclear spin states, the latter to provide a model solid-state system for quantum computation. Imaging applications include the imaging of single biomolecules and the subsurface imaging of electronic devices. The project will greatly expand our educational efforts in nanoscience and nanotechnology, providing research training of undergraduate and graduate students, including female and minority students at the University of Texas at Austin, and establishing a new pool of highly capable scientists. The effort will also provide research projects for students in our UTeach Master's in Physics Education program, which has been proven to produce and retain more highly qualified high school science teachers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Optically Switchable Metal Hydride Films: Properties and Structures
-
批准号:0072365
-
项目类别:Continuing Grant
-
资助金额:$18.0万
-
财政年份:2000
-
负责人:John Markert
-
依托单位:
Magnetism, Superconductivity and Anisotropy in Unusual Materials and Structures
-
批准号:9705414
-
项目类别:Continuing Grant
-
资助金额:$18.45万
-
财政年份:1997
-
负责人:John Markert
-
依托单位:
Presidential Young Investigator Award
-
批准号:9158089
-
项目类别:Continuing Grant
-
资助金额:$32.75万
-
财政年份:1991
-
负责人:John Markert
-
依托单位:
国内基金
海外基金
Capture and Release of Droplets Using Advanced Materials for High Technology Applications
-
批准号:52073127
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2020
-
负责人:Alidad Amirfazli
-
依托单位:
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
-
批准号:31070748
-
项目类别:面上项目
-
资助金额:34.0万元
-
批准年份:2010
-
负责人:Christine Nardini
-
依托单位: