NIRT: Active Nanostructure Enabled On-Chip Spectroscopy System for Cancer Detection

0608934Park该项目的目标是开发一种用于癌症检测的片上光谱系统。该项目可能对治疗黑色素瘤产生影响，黑色素瘤是研究人员关注的早期发现的癌症。拟议的目标是使用附着在DNA探针上的纳米探针作为生物标志物检测的工具，这将实现紧凑的芯片上检测系统，该系统将提供高度准确且廉价的血液检测。计划中的设备将适用于医生办公室，而不仅仅是医院。该系统的重要组成部分将是一个可调谐的负折射率光子晶体。通过对薄膜的机械拉伸，将在嵌入聚合物介质中的Si纳米棒PC组装中实现可调谐性。 更广泛的影响将体现在纳米技术和学生培训方面，特别是在代表性不足的少数民族的参与方面。

0608934Park The goal of the project is to develop an on-chip spectroscopy system for cancer detection. The project can have impact on treating melanoma, which is the cancer that the investigators have focused on for early detection. The proposed goal is to use nanoprobes attached to DNA probes as a tool for biomarker detection which will enable a compact on-chip detection system that will provide a highly accurate and inexpensive blood test. The planned device will be suitable for use in physicians' offices rather than only at hospitals. The important component of the system will be a tunable negative refractive index photonic crystal. Tunability will be achieved in Si nano-rods PC assembly embedded in polymeric medium by mechanical stretching of the film. The broader impacts will be in terms of nanotechnology and student training, especially in involvement of underrepresented minorities.