STTR Phase I: Magnetohydrodynamic-based Circular Liquid Chromatography

这个小企业技术转让（STTR）第一阶段项目旨在开发基于磁流体动力学（MHD）的闭环液相色谱（LC）技术。这项工作将改进现有技术，以实现对所需材料的更具体的纯化。 现有LC由固定长度的列组成，无法根据所考虑的分离任务进行调整。 液相色谱是一种成熟的技术，常用于化学、生物和医学实验室中大分子的分离和纯化。液相色谱法是一种高效液相色谱技术，它的优点是在分离和纯化过程中不需要分离器，而在分离过程中，色谱柱的长度是无限长的。固定长度柱的缺点早已被认识到。 这种新的MHD方法将允许增加分离，从而更好地纯化这些大分子，用作研究试剂以及药物开发市场。

This Small Business Technology Transfer (STTR) Phase I project aims to develop a magnetohydrodynamically (MHD) based, closed-loop liquid chromatographic (LC) technology. The work will improve on exiting technologies to allow more specific purification of desired materials. Existing LCs consist of a fixed length column that cannot adjust according to the separation task in mind. Using a column bent into a closed loop that has virtual infinite length and should allow one to achieve very precise separations and purification of compounds will alleviate the MHD system.Liquid chromatography is a mature technology that is often used in chemical, biological, and medical laboratories for separation and purification of macromolecules. The shortcomings of fixed length columns have long been recognized. This novel MHD approach will allow for increased separation and thus better purification of such macromolecules for use as research reagents as well as in the drug development market.