CAREER: Water-Soluble Phosphine Ligands and Catalysis

该职业奖由无机、生物无机和有机金属化学项目颁发，支持内华达大学里诺分校布赖恩·j·弗罗斯特教授研究开发新的手性膦配体和环境友好型催化剂的工作。该项目的重点是设计和合成新型水溶性膦配体，并在水和/或双相介质中开发催化反应，如加氢和C-C偶联反应。由于水具有环保、廉价、无毒和不可燃的特点，因此具有深远的健康和安全效益，因此预计在未来的工业过程中，水作为溶剂将变得越来越重要。该项目可能为水相催化领域提供科学基础和工业相关的进展；比如利用pH值来调节反应性。该提案的教育方面侧重于改善内华达州瓦肖县学区的K-12科学教育。该项目将提供教师讲习班，并在学年期间通过科学伙伴计划将本科生送到教室。除了研究活动，参与该项目的本科生和研究生将有机会参与准备和制作一个名为“这不是魔术，这是科学！”的化学演示节目，为内华达州北部的K-12学生表演。

This CAREER award by the Inorganic, Bioinorganic and Organometallic Chemistry program supports the work of Professor Brian J. Frost at the University of Nevada, Reno to study the development of new chiral phosphine ligands and environmentally friendly catalysts. The project centers on the design and synthesis of novel water-soluble phosphine ligands and the development of catalytic reactions, such as hydrogenation and C-C coupling reactions, in aqueous and/or biphasic media. Water is expected to become increasingly important as a solvent in future industrial processes as it is environmentally friendly, inexpensive, nontoxic, and nonflammable, and thus, presents far-reaching health and safety benefits. This project may provide scientifically fundamental and industrially relevant advances in the field of aqueous-phase catalysis; such as the utilization of pH to modulate reactivity. The educational aspect of this proposal focuses on improvements in K-12 science education in the Washoe County School District of Nevada. This program will provide teacher workshops, and will send undergraduate students out into the classrooms during the academic year via the Science Partners Program. In addition to research activities, undergraduate andgraduate students involved in this project will have the opportunity to participate in the preparation and production of a chemistry demonstration show entitled, "It's not magic, it's SCIENCE!" performed for K-12 students in northern Nevada.