Fragment Based Screening for new Antibiotics by Protein X-Ray Crystallography

部分由于抗生素耐药性水平的上升，预计致病细菌的死亡人数将在未来15年内飙升。因此，迫切需要新的抗生素来治疗细菌感染。该项目将使用一种相对较新的发现工具，称为基于片段的筛选，以发现新一代抗菌剂。这一工具将使新药的快速经济发现成为可能，并将补充澳大利亚生物技术基础设施的其他投资。

Due in part to rising levels of antibiotic resistance, the death toll from pathogenic bacteria is expected to skyrocket over the next 15 years. There is therefore a pressing need for new antibiotics to treat bacterial infection. This project will use a relatively new discovery tool called fragment based screening to discover a new generation of antibacterial agents. This tool will allow for the rapid economical discovery of new drugs, and will complement other investments in Australian biotechnology infrastructure.