SGER: Innovative Fabrication of Microporous Surfaces With Nano-Roughness on Titanium Biomedical Implants

该项目将在马里兰大学园区分校进行，研究生物医用钛植入物上具有纳米粗糙度的微孔表面的创新制造。目前的生物医学植入物，如髋关节，寿命很低，只有10到15年。寿命低的主要原因之一是种植体与骨之间的界面结合强度较差。该项目通过在钛植入材料上创建具有纳米粗糙度的受控微孔表面来解决这一问题，以便骨骼可以在这些表面上生长，从而显着增加互锁。具体目标包括通过创新的等离子处理技术从钛表面雕刻出微孔表面。此外，微孔表面将通过等离子体技术或聚合技术进行纳米粗化。该项目具有突出的更广泛的影响。该项目的成功完成将带来新的、未经测试的制造技术，以改善互锁，增加种植体-骨界面的强度。当这些技术适应当前的生物医学植入物时，植入物的寿命可以显著增加，超过目前的10到15年的限制。这将大大提高生活质量，同时降低医疗成本。此外，一名研究生将接受这一项目的培训，以增加能够在这一方向进行进一步研究和/或帮助生物医学植入行业的科学家队伍。

The project to be carried out at the University of Maryland, College Park deals with innovative fabrication of microporous surfaces with nano-roughness on biomedical titanium implants. Present biomedical implants such as hip joints have low longevity of 10 to 15 years. One of the primary reasons for low longevity is poor interfacial bonding strength between the implant and the bone. This project addresses this problem by creating controlled microporous surfaces with nano-roughness on titanium implant materials so that bone can grow onto these surfaces thereby significantly increasing the interlocking. The specific goals include fabrication of microporous surfaces by carving out from the titanium surface by innovative plasma processing techniques. Further the microporous surfaces will be nano-roughened either by plasma techniques or polymerization techniques.This project has outstanding broader impacts. A successful completion of this project will result in new, untested fabrication techniques to improve interlocking, increasing the strength of the implant-bone interfaces. When these techniques are adapted to current biomedical implants, the longevity of the implants can be significantly increased beyond the current limit of 10 to 15 years. This will greatly improve the quality of life and at the same time reduce health care costs. Further, a graduate student will be trained in this project adding to the pool of scientists who can carry out further research in this direction and/or help the biomedical implant industry.