Mechanisms of nitrogen and phosphorus activation and functionalization

该奖项由无机、生物无机和有机金属化学项目颁发，支持塔夫茨大学Elena V. rybakakakimova教授建立过渡金属辅助氮和磷解理、活化和功能化机制的工作。该研究的主要重点是能够分裂二氮的低坐标、高活性钼（III）配合物的动力学研究（低温、停流快速反应研究）。拟议的研究将有助于设计新的工艺，将氮从二氮直接纳入有机或无机分子，而不需要氨的中间作用。从这些研究中获得的理解将用于推动对磷的类似过程的发现。有机磷化合物在催化、杀虫剂和酶抑制剂中都是重要的配体。本科生、研究生和博士后研究人员将与麻省理工学院和迈阿密大学的科学家合作。Rybak-Akimova博士是一位运动专家，与许多美国和国际科学家一起使用nsf资助的止流仪器。

This award by the Inorganic, Bioinorganic, and Organometallic Chemistry Program supports the work of Professor Elena V. Rybak-Akimova at Tufts University to establish the mechanisms of transition metal assisted cleavage, activation, and functionalization of nitrogen and phosphorus. The major emphasis of the research is on kinetic studies (low-temperature, stopped-flow investigations of rapid reactions) of low coordinate, highly reactive molybdenum(III) complexes that are capable of splitting dinitrogen. The proposed research will contribute to the design of new processes that incorporate nitrogen, from dinitrogen, directly into organic or inorganic molecules without requiring the intermediacy of ammonia. The understanding garnered from these studies will be used to drive the discovery of analogous processes for phosphorus. Organic phosphorus compounds are important as ligands in catalysis and also in insecticides and enzyme inhibitors. Undergraduate, graduate, and postdoctoral researchers will collaborate with scientists at both MIT and the University of Miami. Dr. Rybak-Akimova, an expert kineticist, works with many U.S. and international scientists using NSF-funded stopped-flow instrumentation.