SBIR Phase II: Ultra-Fast Software Image Reconstruction for Micro-CT

SBIR第二期项目旨在开发一个软件包，使x射线微型ct（计算机断层扫描）成像的快速图像重建成为可能。在过去的几年里，Micro-CT已经成为制药和基础研究中非常有价值的工具。目前的Micro-CT扫描仪已达到1微米的分辨率，因此可以对小动物如小鼠的整体进行高分辨率的体内和离体三维检查。Micro-CT的其他应用范围从功能成像到材料科学。然而，单一数据集的高分辨率重建可能非常耗时，从而限制了使用。如果能够开发出能够将图像重建速度提高2到3个数量级的分析软件，将大大减少分析高分辨率Micro-CT图像的时间，从而提高这一强大成像方法的实用性。

The SBIR Phase II project aims to develop a software package that enables rapid image reconstruction for X-ray Micro-CT (computerized Tomography) imaging. Over the last few years, Micro-CT has become a very valuable tool in pharmaceutical and basic research. Current Micro-CT scanners have reached a resolution of 1 micrometer and thus allow high resolution in-vivo and ex-vivo three dimensional examination of entire small animals such as mice. Other applications of Micro-CT range from functional imaging to use in material science. Yet, high resolution reconstruction of a single data set can be extremely time intensive, thus limiting the use. If analysis software capable of speeding up image reconstruction by 2 or 3 orders of magnitude can be developed, such software would significantly decrease the time to analyze high-resolution Micro-CT images and would thus increase the utility of this powerful imaging method.