Organo-f-Element Chemistry: Integrated Synthetic, Mechanistic, Catalytic, and Thermochemical Studies

这一奖项由无机化学、生物无机化学和金属有机化学项目授予西北大学的Tobin J.Marks教授，支持对涉及稀土和相关早期过渡金属的新催化转化的基础和面向技术方面的研究。该提议分为四个子主题：1)探索性催化金属-杂元素化学，2)有机稀土介体材料合成，3)多核催化，4)其他金属和支撑配体用于f元素催化。滴定量热法将被用来量化金属-配体单键和多键的强度，并在绝对尺度上“锚定”键热。这些研究包括选择性的C-N、C-O、C-S和C-P成键过程的研究，一系列前体结构的研究，反应速率、选择性和取代基效应的表征，以及分子内和分子间过程的比较。这些转变可能会产生高效、原子经济的催化过程，用于生产燃料、塑料、药品和其他具有商业重要性的化学品。这项研究还解决了国家对受过核工业基础重元素化学培训的研究人员的需求。

This award by the Inorganic, Bioinorganic, and Organometallic Chemistry Program to Professor Tobin J. Marks of Northwestern University supports studies on both fundamental and technologically-oriented aspects of new catalytic transformations involving lanthanide and related early transition metals. The proposal has been divided into four subtopics: 1) exploratory catalytic metal-heteroelement chemistry, 2) organolanthanide-mediated materials synthesis, 3) multinuclear catalysis and 4) other metals and supporting ligands for f-element catalysis. Titration calorimetry will be used to quantify the strengths of metal-ligand single and multiple bonds and to "anchor" bond enthalpies on an absolute scale. The research includes the study of selective C-N, C-O, C-S, and C-P bond-forming processes, the study of a range of precursor structures, the characterization of reaction rates, selectivities, and substituent effects, as well as the comparison of intramolecular vs. intermolecular processes. These transformations may produce efficient, atom-economical, catalytic processes for the production of fuels, plastics, pharmaceuticals and other commercially-important chemicals. This research also addresses the national need for researchers trained in basic heavy element chemistry for the nuclear industry.