Bayesian Phylogenetic Diagnostics (BPD): Tools and Analyses for the Diagnosis of Convergence in Bayesian Inference of Phylogeny

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。佛罗里达州立大学获得了开发软件进行系统发育分析的奖项。系统发生软件帮助研究人员了解物种之间的进化关系。系统发育估计形成了大多数现代生物学研究的基础，并帮助框架研究人员？政策制定者？了解这个星球上生命的分布、多样性和保护。该系统将整合现有的和新的收敛算法，并帮助研究人员分析和可视化遗传算法。融合研究和软件将在现代高性能计算平台上开发。该团队将采取两级方法，即，在本地计算资源上进行原型分析和软件，然后扩大到大型国家计算资源，如TeraGrid。如果生命科学界的成员要有效地利用未来三年内联机的千万亿次计算资源，现在就必须展示这种方法。Bayesian Phylogenetics Diagnostics软件包将作为可下载应用程序、网络应用程序和网络服务提供，并将与TeraGrid、CIPRES和iPlant等其他服务集成。该软件包将与系统发育软件包实时集成，让用户直接了解分析的潜在问题。大量的输入和输出格式将允许该软件包与其他系统发育软件包、统计分析和可视化软件交换数据。有关该项目的更多信息可在http://ceb.sc.fsu.edu/bpd上找到。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Florida State University has received an award to develop software to conduct phylogenetic analysis. Phylogenetic software helps researchers to understand the evolutionary relationship among species. Phylogeny estimation forms the foundation to most modern biological studies and helps frame researchers? and policy makers? understanding of the distribution, diversity, and conservation of life on this planet. The system will integrate existing and new algorithms of convergence and help researchers analyze and visualize phylogenies. The convergence study and software will be developed over modern high performance computing platforms. The team will take a two-tiered approach, i.e., prototype analyses and software on local computing resources and then scale up to large national computing resources, such as, TeraGrid. It is critical to demonstrate this approach now if members of the life sciences community are to effectively utilize the petascale computing resources being brought on-line in the next three years. The Bayesian Phylogenetics Diagnostics package will be available as a downloadable application, as a web application, as a web service and will be integrated with other services such as the TeraGrid, CIPRES and iPlant. This package will integrate in real-time with phylogenetic packages to give users direct insight into potential problems with the analysis. A large number of input and output formats will allow the package to exchange data with additional phylogenetic packages, statistical analysis and visualization software. Additional information about the project can be found at http://ceb.sc.fsu.edu/bpd.