Chemical Mechanisms of Reactive Sulfur Species

在这个由化学部无机、生物无机和有机金属化学项目资助的项目中，俄克拉何马大学的Michael T. Ashby将研究与生物抗菌过程有关的基本化学成分硫的反应机制。对生理条件下硫的反应性的了解非常有限，即使它们与细胞损伤过程有关。从这些研究中获得的信息将在生物/医学领域得到应用，这些研究也将增强硫化学的基础知识。PI将参与研究生和博士后培训，并在扩大化学领域代表性不足群体的参与方面有着良好的记录。

In this project funded by the Inorganic, Bioinorganic, and Organometallic Chemistry Program of the Chemistry Division, Michael T. Ashby of the University of Oklahoma will study the reaction mechanisms of sulfur species of fundamental chemical interest that are implicated in biological antimicrobial processes. The understanding of sulfur species reactivity under physiological conditions is very limited, even though they are implicated in cellular damage processes. The information gained from these studies will find application in biological/medical fields, and such studies will also enhance fundamental knowledge of sulfur chemistry. The PI will be involved in graduate student and postdoctoral training and has a track record of broadening the participation of underrepresented groups in chemistry.