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Renovation of Chemistry Research Laboratories at Trinity College

Renovation of Chemistry Research Laboratories at Trinity College
三一学院化学研究实验室改造
批准号:
0963165
负责人:
Timothy Curran
金额:
$74.62万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-15 至 2012-08-31

项目摘要

项目成果

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中文摘要
翻译
该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。该奖项资助了三一学院化学系五位活跃的研究人员所使用的实验室空间的翻新,以便他们能够进行现代化学研究。这五个学院使用的实验室是1937年为研究而设计的,但设备并不完善,无法满足现代化学研究的要求。特别是,这些实验室缺乏对温度、湿度和阳光的控制。目前的研究项目将通过改造得到加强,包括使用有机金属部分来限制肽的特定二级结构,骨蛋白骨钙素的生物学特性和蛋白质与DNA的结合,巴克敏斯特富勒烯和相关化合物的合理合成,过渡金属氢化物的反应性,以及活性氧在与神经元细胞死亡相关的分子事件中的作用。改造完成后,将消除阻碍受影响的五个教员在实验室取得成就的障碍,并使这些教员能够继续与大量本科生研究人员合作。
英文摘要
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award funds the renovation of laboratory spaces used by five active researchers in the Chemistry Department at Trinity College so they can handle modern, chemical research. Designed for research in 1937, the laboratories used by these five faculty are not well-equipped to handle the demands of modern chemical research. In particular, these laboratories lack control of temperature, humidity and sunlight. Current research projects which will be enhanced by the renovation include work on the use of organometallic moieties to constrain peptides to particular secondary structures, the biological properties of the bone protein osteocalcin and the binding of proteins to DNA, rational syntheses for Buckminsterfullerene and related compounds, the reactivity of transition metal hydrides, and the role of reactive oxygen species in the molecular events associated with neuronal cell death. When completed, the renovations will remove obstacles that slow the pace of accomplishment in the laboratories of the five affected faculty and allow these faculty to continue working with large numbers of undergraduate student researchers.
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