MRI: Acquisition of a 400 MHz NMR Spectrometer

MRI：购买 400 MHz NMR 波谱仪

• 批准号: 0619275
• 负责人: Timothy Curran
• 金额: $ 30.8万
• 依托单位: Trinity College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619275&HistoricalAwards=false
• 关键词: MRI; Acquisition; 400; MHz; NMR

With support from the Major Research Instrumentation (MRI) Acquisition Program, the Department of Chemistry at Trinity College (Hartford CT.) will acquire a 400 MHz NMR spectrometer. This instrument will allow researchers to advance their investigations on, a) the conformational behavior of tungsten-alkynylpeptides, b) the conformational behavior of ferrocenylcyclicpeptides, c) the synthesis of osteocalcin peptides, d) the conformational behavior of capsaicin, e) the binding of metals to oligonucleotides, f) carbon-carbon bond forming reactions mediated by indium, g) synthesis of enediyne and epoxydiynes, h) the oxygen transfer chemistry of rhenium-oxo complexes, and i) the structure of metal polyhydride complexes.Nuclear Magnetic Resonance (NMR) Spectroscopy is the most widely used tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances and to provide information on the arrangement and connectivity of atoms in molecules. Dynamical information is obtained providing insight on the motions of molecules. This award will provide essential analytical capabilities to faculty and students. It is vital to the chemistry curriculum where students are introduced to NMR and use it in their laboratory courses.

在主要研究仪器（MRI）采购计划的支持下，Trinity College（Hartford CT.）的化学系将获得一台400兆赫核磁共振光谱仪 该仪器将使研究人员能够推进他们对以下方面的研究：a）钨-炔基肽的构象行为，B）二茂铁基环肽的构象行为，c）骨钙素肽的合成，d）辣椒素的构象行为，e）金属与寡核苷酸的结合，f）铟介导的碳-碳键形成反应，g）烯二炔和环氧二炔的合成，h）金属-氧代络合物的氧转移化学; i）金属多氢化物络合物的结构。核磁共振（NMR）光谱是化学家用于阐明分子结构的最广泛使用的工具。 它用于识别未知物质，并提供有关分子中原子排列和连接的信息。 获得动力学信息，提供对分子运动的洞察。 该奖项将为教师和学生提供必要的分析能力。 这是至关重要的化学课程，学生介绍核磁共振和使用它在他们的实验室课程。