Center for Pharmaceutical Development

0968003佐治亚理工学院；Andy Bommarius 0968972堪萨斯大学；Eric Munson这项提议的目的是启动一个新的I/UCRC“制药制造和配方”(CPMF)，专注于应对制药业当前的挑战，并开发解决方案，朝着更具选择性和健壮的制造工艺、更稳定的配方以及更具特性和一致性的产品发展。拟建中心的牵头机构是佐治亚理工学院，选址在堪萨斯大学。CPMF建议探索对药品制造和改进药品配方重要的领域。该中心计划开发方法和技术，以生产更好的药物，使其使用更长时间，更有效，更安全。通过联合佐治亚理工学院、杜肯大学和堪萨斯大学的努力，私人投资机构提出了一些潜在的重要项目，这些项目可以显著促进制造更好的药物所需的应用知识。CPMF将允许制药公司以一种低成本的方法以合作的方式推进高风险研究，以便能够在分担风险和互惠互利的情况下追求重要的制造需求和创新。CPMF已经召集了一个非常强大的研究小组，他们非常有资格执行提案中概述的研究。拟议的中心将促进安全有效的药物和药物配方的快速发展，并将发现拟议药物配方的潜在问题，具有改善甚至拯救人类生命的潜力。该中心计划让研究生和博士后同事参与他们的研究并展示他们的研究，从而为他们创造一个与制药和医疗领域的同行互动的机会。传播结果的计划是经过深思熟虑的，受众是适当的。拟议的中心还计划将重点放在招聘代表性不足的群体上。

0968003 Georgia Tech; Andy Bommarius 0968972 University of Kansas; Eric Munson The purpose of this proposal is to start a new I/UCRC "Pharmaceutical Manufacturing and Formulation" (CPMF) with a focus on addressing current challenges in the pharmaceutical industry, and developing solutions towards more selective and robust manufacturing processes, more stable formulations, and better characterized and consistent products. The lead institution of the proposed Center is Georgia Tech with a site location at the University of Kansas. CPMF proposes to explore areas important to pharmaceutical manufacturing and improved formulations for pharmaceuticals. The Center plans to develop methods and technologies that will produce better pharmaceuticals, make them last longer, be more effective, and safer. By combining the efforts of Georgia Tech, Duquesne University and the University of Kansas, the PIs have proposed a number of potentially important projects that could significantly advance the applied knowledge necessary to make better pharmaceuticals. CPMF will allow pharmaceutical companies a lower cost approach to advancing risky research in a cooperative manner such that important manufacturing needs and innovations can be pursued with shared risk and mutual gain. CPMF has assembled a very strong group of researchers who are well-qualified to perform the research outlined in the proposal. The proposed Center will promote the rapid development of safe and efficacious drugs and drug formulations, and will identify potential problems with proposed drug formulations, with the potential of improving or even saving human lives. The Center plans to involve graduate students and post-doctoral associates in performing and presenting their research, thereby creating an opportunity for them to interact with counterparts from pharmaceutical and medical areas. Plans for dissemination of results are well thought out and audiences are appropriate. The proposed Center also plans to put emphasis on recruiting under-represented groups.