Further Discovery and Elaboration of Metallacrowns

化学结构，动力学和机制计划支持教授文森特L。Pecoraro在美国密歇根大学安娜堡分校，他的研究重点是金属冠的发展，金属基分子识别剂，最终可能用于实际重要的应用。两个关键目标指导金属冠的研究。第一个是了解这些主体与固态和溶液中的各种客体的分子识别。Pecoraro教授希望利用手性金属冠空腔内的环境进行催化化学转化。第二个目标是利用金属冠醚的固态性质来制备手性、软非线性光学材料、多孔固体和分子磁体。Pecoraro教授在美国国家科学基金会化学部化学结构、动力学和机制计划的支持下，探索了分子磁体作为分子识别剂、催化剂、光学材料和分子磁体的用途。这项工作的具体目标是使用这些材料作为催化剂，以及为显示二次谐波产生的非线性光学材料应用的客人的光学透明的手性隔室的设计。教授pecoraro将继续在各级生产科学家和指导妇女和少数民族在他的实验室和部门的良好记录。PI是密歇根州化学生物界面培训计划的主任，该计划指导第二和第三年的研究生，并有大约17%的少数民族参与和50%的女性学员。该培训计划的目的是交叉培训学生在化学和生物学。

The Chemical Structure, Dynamics and Mechanisms Program supports Professor Vincent L. Pecoraro at the University of Michigan-Ann Arbor whose research emphasizes the development of metallacrowns, metal-based molecular recognition agents that may eventually be used in applications of practical importance. Two key objectives guide the metallacrown research. The first is to understand molecular recognition of these hosts with a variety of guests in the solid state and in solution. Professor Pecoraro hopes to exploit the environment within chiral metallacrown cavities to carry out catalytic chemical transformations. The second objective seeks to exploit the solid state properties of metallacrowns to make chiral, soft non-linear optical materials, porous solids, and molecular magnets. The proposed molecular magnets, if successful, would revolutionize data storage and provide greater fundamental insight on magnetic phenomena.With the support of the Chemical Structure, Dynamics and Mechanisms Program in the Chemistry Division at the National Science Foundation, Professor Pecoraro explores the utility of metallocrowns as molecular recognition agents, catalysts, optical materials and molecular magnets. This work specifically targets the use of these materials as catalysts as well for the design of optically transparent chiral compartments for guests that display second harmonic generation for nonlinear optical materials applications. Professor Pecoraro will continue an excellent track record for producing scientists at all levels and for mentoring women and minorities in both his laboratory and the department. The PI is the Director of the Michigan Chemistry Biology Interface Training Program, which mentors second and third year graduate students and has had about 17% minority participation and 50% female trainees. The intent of this training program is to cross train students in chemistry and biology.