Metallacrowns: A New Class of Metallamacrocycles

无机化学、生物无机化学和金属有机化学项目的这一奖项支持密歇根大学文森特·L·佩科拉罗教授在金属大环化合物合成方面的研究，金属大环化合物利用金属离子作为围绕中心金属离子的环状结构的一部分。目标包括手性金属冠合物的制备、手性金属冠合物对手性客体分子的选择性识别以及手性固体的模块化合成。手性或不对称分子在生物学中自然存在，在新药合成中也很重要，在新药合成中必须定量制备不同手性的分子。本研究致力于创造可用于手性分子分离的新方法的分子识别剂。

This award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research by Professor Vincent L. Pecoraro at the University of Michigan on the synthesis of metallomacrocyclic complexes, which utilize metal ions as part of a cyclic structure surrounding a central metal ion. Goals include the preparation of chiral metallacrown complexes, selective recognition of chiral guest molecules by metallacrown complexes and the modular synthesis of chiral solids. Chiral or asymmetric molecules occur naturally in biology and are also important in new drug synthesis where molecules of different chiralities must be quantatively prepared. This research focuses on creating molecular recognition agents that may be employed in new methods for the separation of chiral molecules.