Metallacrowns: A New Class of Metallamacrocycles

金属大环：一类新的金属大环化合物

• 批准号: 0111428
• 负责人: Vincent Pecoraro
• 金额: $ 42.3万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0111428&HistoricalAwards=false
• 关键词: Metallacrowns; New; Class; Metallamacrocycles

This award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research by Professor Vincent L. Pecoraro at the University of Michigan on the synthesis of metallomacrocyclic complexes, which utilize metal ions as part of a cyclic structure surrounding a central metal ion. Goals include the preparation of chiral metallacrown complexes, selective recognition of chiral guest molecules by metallacrown complexes and the modular synthesis of chiral solids. Chiral or asymmetric molecules occur naturally in biology and are also important in new drug synthesis where molecules of different chiralities must be quantatively prepared. This research focuses on creating molecular recognition agents that may be employed in new methods for the separation of chiral molecules.

这个无机、生物无机和有机金属化学项目的奖项支持密歇根大学Vincent L. Pecoraro教授关于金属大环配合物合成的研究，这种配合物利用金属离子作为围绕中心金属离子的环结构的一部分。目标包括手性金属冠配合物的制备，金属冠配合物对手性客体分子的选择性识别以及手性固体的模块化合成。手性或不对称分子在生物学中自然存在，在新药合成中也很重要，其中必须定量制备不同手性的分子。本研究的重点是创建分子识别剂，可用于手性分子分离的新方法。