Integrating Bioinformatics into the Life Sciences - Phase 2

内布拉斯加大学奥马哈分校、内布拉斯加大学科尔尼分校和内布拉斯加卫斯理大学这三所内布拉斯加大学结成伙伴关系，正在制定和实施以生物信息学为重点的生命科学课程实验室练习。 该项目建立在以前的NSF资助的工作，增加生物信息学内容的讲座课程。 讲座材料，学生实验室模块和开发的工具，以帮助学生使用生物信息学数据库都免费提供由PI维护和更新的网站（ccli.ist.unomaha.edu）。 该项目的智力价值在于它有可能使各级学生了解生物信息学作为一门学科的潜力，以及所提出的问题和产生的模块的有趣主题。 后者包括尼安德特人基因序列分析和使用蛋白质分析来揭示地球上生命的历史等主题。 更广泛的影响在于通过在以前制定的讲座内容中增加基于探究的实验室所产生的协同作用，以便为生命科学的各级生物信息学教育奠定基础，并制定传播计划，包括与出版商合作，将模块版本作为补充材料纳入其教科书。

A partnership of three Nebraska institutions--the University of Nebraska at Omaha, the University of Nebraska at Kearney and Nebraska Wesleyan University--are developing and implementing bioinformatics-focused laboratory exercises across the life sciences curriculum. The project builds on previous NSF-funded work to add bioinformatics content to lecture courses. The lecture material, the student laboratory modules and the tools developed to help students use bioinformatics databases are all freely available at a website maintained and updated by the PIs (http://ccli.ist.unomaha.edu). The intellectual merit of this project resides in its potential to enable students at all levels to understand the potential of bioinformatics as a discipline and in the interesting subject matter of the problems posed and modules produced. These latter include such subjects as analysis of Neanderthal gene sequences and using protein analysis to unravel the history of life on earth. Broader impacts lie in the synergism created by adding inquiry-based laboratories to previously developed lecture content in order to provide a foundation of bioinformatics education at all levels in the life sciences and a dissemination plan that includes partnering with publishers to include versions of the modules as supplementary materials in their textbooks.