Collaborative Research: Hybrid Integration of Plasmonic Interferometer Sensors and Active Optoelectronic Devices on a Single Microfluidic Chip

该计划的目标是通过在单个微流体芯片上混合集成无源等离子体干涉仪和Si波导阵列耦合有源光电器件来创建高度集成的传感器系统，用于低成本，实时，无标签，无透镜和多路复用传感应用。所提出的设备提供了一种用于护理点诊断的紧凑且便携的感测解决方案，该解决方案目前不存在，但是对于克服传统角度可调的传感器的尺寸和成本障碍是至关重要的，其智能优点是将芯片级半导体光源和检测器与等离子体传感器集成在单个芯片上，使得光不需要耦合到/从传感器中分离出来进行分析。垂直等离子体干涉仪将通过在单个波长处的强度询问来执行感测功能。弯曲的硅波导被提出来互连有源光电器件和等离子体干涉仪，并通过防止未耦合的光进入检测器来增强传感器性能。此外，还将研究在芯片上消除温度引起的信号漂移的新方法。更广泛的影响是研究芯片级一体化传感器平台，并整合研究和教育。拟议研究的结果将对生物传感、医疗保健和国家需求产生巨大的长期影响。教育和推广计划的主要目标是提高PI？该计划旨在提高研究生和本科生对纳米光子学和生物光子学前沿研究的参与，并为科学、技术、工程和数学学科中代表性不足的群体提供机会。

The objective of this program is to create a highly integrated sensor system through hybrid integration of passive plasmonic interferometers and Si waveguide array coupled active optoelectronic devices on a single microfluidic chip for low cost, real-time, label-free, lens-free, and multiplexed sensing applications. The proposed device provides a compact and portable sensing solution for point-of-care diagnostics that does not currently exist but is critical for overcoming size and cost barriers of conventional angular-tunable, prism-based surface plasmon resonance systems.The intellectual merit is to integrate chip-scale semiconductor light sources and detectors with plasmonic sensors on a single chip so that light does not need to be coupled into/out of the sensors for analysis. Vertical plasmonic interferometers will perform the sensing function through intensity interrogation at a single wavelength. Curved silicon waveguides are proposed to interconnect active optoelectronic devices and plasmonic interferometers and enhance the sensor performance by preventing uncoupled light from entering the detector. Novel methods to obtain on-chip cancellation of temperature-induced signal drift will also be investigated.The broader impacts are to investigate chip-scale all-in-one sensor platforms and integrate research and education. The outcome of the proposed research will have enormous long-term impacts on biosensing, health care and the national needs. The main goals of the education and outreach program are to enhance the PIs? undergraduate laboratory courses, improve the participation of graduate and undergraduate students in cutting-edge research in nanophotonics and biophotonics, and provide opportunities for under-represented groups in science, technology, engineering, and mathematics disciplines.