CSR-CSI: Software Environment for Real-Time Non-Rigid Registration using Commodity and Grid Computing

在这个项目中，我们将集中在四个重要方面（要求）的一个端到端的软件环境，执行多个并行非刚性登记的网格。我们的应用程序是图像引导神经外科（IGNS）。 IGNS是神经外科手术的重要工具，神经外科手术是治疗恶性脑肿瘤的常用治疗手段，本项目将研究的四个要求是：（1）高性能 的 的 平行 和 分布式 非刚性套准码通过动态平衡处理器的工作负荷， 易用性 医生 （放射科医生） 通过为我们的网络服务的客户开发图形用户界面（GUI）来实现网络服务的可移植性（3）代码的可移植性，以便从一个高端工作站运行到研究医院和医疗中心可用的局域网和广域网内的多个工作站集群，（4）可靠性，通过保证系统的这一部分将完成图像配准的计算，并通过在运行时获取和重新配置系统以补偿丢失（故障）来确保我们满足时间约束。最终产品将是IGNS网络服务的原型。然而，该项目将对图像引导治疗产生更广泛的影响，因为相同的框架（但不同的模态和有限元近似模型）可用于前列腺活检和治疗以及肝脏冷冻治疗。

In this project we will focus on four important aspects (requirements)of an end-to-end software environment for performing multiple parallelnon-rigid registrations over the Grid. Our application is Image GuidedNeurosurgery (IGNS). IGNS is an important tool for neurosurgicalresection which is a common therapeutic intervention in the treatmentof malignant brain tumors.The four requirements we will study in this project are: (1) thehigh-performance of the parallel and distributed non-rigidregistration code by dynamically balancing the processors work-load,(2) the ease-of-use from medical doctors (radiologist) of aweb-service by developing a Graphical User Interface (GUI) for clientsof our web-service (3) the portability of the code to run from asingle high-end workstation to more than one clusters of workstationswithin the local and wide area networks available to researchhospitals and medical centers, (4) the reliability by guaranteeingthat part of the system will complete the computations for the imageregistration and by making sure we meet the time constrains byacquiring and re-configuring the system at runtime to compensate forlost (faulty) computing resources.The end-product will be a prototype of an IGNS web-service. However,this project will have broader impact to image guided therapy becausethe same framework (but different modalities and finite elementapproximation models) can be used in prostate biopsy and treatment,and liver cryotherapy.