NDR1: A Point of Convergence in Stress and Pathogen Signaling in Arabidopsis Thaliana.

植物不断地暴露在压力下，但它们已经进化出许多机制，在一些最恶劣的条件下做出反应、适应并茁壮成长。在大多数情况下，适应压力的能力，无论是来自环境(非生物的)还是捕食者(生物的)，仅仅需要“资源的重新分配”。例如，在干旱条件下，植物下调生长和发育的调控，这两个过程都是耗能的过程，有利于最大限度地减少水分损失。同样，当植物受到病原体感染时，首要目标是限制病原体获取营养。这个项目试图了解植物如何利用基本的生理过程来应对压力。为此，该项目将研究生物胁迫信号是如何被激活和调节的，以及这个信号过程是如何与一般寄主生理和植物健康联系在一起的。首席研究员假设，与人类相似的方式，植物利用机制整合环境和病原体相关的胁迫信号反应。这个项目的目标是了解非生物和生物胁迫信号是如何共同调节的，并开发一个模型，说明植物如何感知周围的世界，处理这些感知到的刺激，最终在各种胁迫条件下生存。这项工作的影响将基本植物健康与环境、病原体的威胁以及总体上的粮食安全联系在一起。该项目包括一个广泛的外展部分。简而言之，一个教学模块将由研究生和博士后研究人员在首席研究员实验室进行，并与密歇根州立大学儿童花园和4H外联计划合作进行。主要的重点将是教育小学生环境、植物健康、食品和可持续发展之间的关系(S)。这一宣传活动的目的是提高年轻人对环境如何影响食物以及最终影响人类健康的认识和理解，并进一步说明人类如何影响环境。

Plants are constantly exposed to stress, yet they have evolved numerous mechanisms to respond, adapt, and thrive under some of the most hostile conditions. In most cases, the ability to adapt to stress, whether from the environment (abiotic) or predators (biotic), simply requires a "reallocation of resources". For example, under conditions of drought, plants down-regulate growth and development, both being energy-expensive processes, in favor of minimizing water loss. Similarly, when plants are infected by pathogens, the primary goal is to restrict pathogen access to nutrients. This project seeks to understand how plants utilize basic physiological processes to respond to stress. To do this, the project will investigate how biotic stress signaling is activated and regulated, and moreover, how this signaling process is interlinked with general host physiology and plant health. The principal investigator hypothesizes that in a manner similar to humans, plants utilize mechanisms to integrate environmental and pathogen-related stress signaling responses. The goal of this project is to understand how abiotic and biotic stress signaling is co-regulated, and to develop a model of how plants sense the world around them, process these perceived stimuli, and ultimately, survive under a variety of stress conditions. The impact of this work links basic plant health to environment, threats from pathogens, and in total, food security.The project includes an extensive outreach component. In short, a teaching module will be conducted by graduate and post-doctoral researchers in principal investigator's lab and carried out in collaboration with the Michigan State University Children's Garden and 4H Outreach Program. The major focus will be to educate elementary school children on the relationship(s) between environment, plant health, food, and sustainability. The goal of this outreach is to increase the awareness and understanding of young people of how food, and ultimately human health, is impacted by the environment, and moreover, to illustrate how humans impact the environment.