MRI Consortium: Acquisition of an Integrated System of Instruments for Multichannel Biopotential Recording of In-vitro and In-vivo Experiments

诺福克州立大学(NSU)被授予建立神经记录和分析的综合研究平台，并为来自电子和光学工程、生物学、计算机科学、纳米技术、免疫学和神经科学领域的学生、教师和相关合作者的研究活动提供资源。将该系统添加到现有的研究基础设施将直接受益并升级研究员S在南加州大学、东弗吉尼亚医学院和老道明大学的研究项目，以及汉普顿路地区的协作网络能力。应用多通道生物电位记录系统，可以在体内和体外测量神经和心脏电位以及神经递质等神经化学物质，并通过嵌入式软件进行分析。该仪器将用于研究各种行为、刺激和疾病条件下相互作用的神经机制。除了生物电位记录，该仪器还将允许通过工程研究开发的神经传感设备的体内评估。此外，感知信号的体内和体外实时测量和监测可以应用于神经疾病和退行性疾病的新治疗策略的开发。这项协同研究的成果将被积极转化为STEM教育和推广目标，特别是在该项目中针对未被充分代表的少数族裔(URM)学生？S领导的机构，美国历史上最大的黑人学院和大学之一。该项目将特别重视汉普顿路地区URM学生的培训，并通过一系列积极的研究将他们的努力扩展到全国的URM学生。利用每个校区现有的外展计划开展培训和外展活动。这个项目的成果将被纳入他们的生物工程辅修课程。此外，他们还将把这一基础设施与新创建的汉普顿道路神经科学网络的活动结合起来。

An award is made to the Norfolk State University (NSU) to build an integrative research platform for neural recording and analysis and provide the resources for students, faculty and associated collaborators for their research activities from electronic and optical engineering, biology, computer science, nanotechnology, immunology, and neuroscience fields. The addition of this system to the existing research infrastructures will directly benefit and upgrade investigator?s research programs at NSU, Eastern Virginia Medical School and Old Dominion University, as well as the collaborative network capabilities in the Hampton Roads area. Applying the multichannel biopotential recording system, neural and cardiac potentials, and neurochemicals such as neurotransmitters can be measured in-vivo and in-vitro, and analyzed by embedded software. The instrument will be applied for the study of neural mechanisms underlying the interactions under various behavioral, stimuli, and disease conditions. In addition to the biopotential recording, the instrumentation will allow in-vivo assessment of neural sensing devices to be developed by engineering research. Furthermore, in-vivo and in-vitro real-time measurement and monitoring of sensing signal can be applied for the development of novel therapeutic treatment strategies of neurological disorders and degeneration.The outcomes of this synergetic research will be positively transferred to achieve their STEM educational and outreach goals, especially focused for under-represented minority (URM) students in the project?s leading institution, NSU, one of the largest Historically Black Colleges and Universities in the U.S. This project will specifically place a high priority on training of URM students in Hampton Roads region and extend their efforts to URM students nationwide through an aggressive set of research, training and outreach activities utilizing current outreach programs on each campus. The outcomes of this project will be incorporated in their Bioengineering Minor program curriculum. Furthermore, they will also integrate this infrastructure with activity of the newly created Hampton Roads Neuroscience Network.