MRI: Acquisition of an X-Ray Diffractometer to Enhance Research and Education at Southeastern New England Colleges

在主要研究仪器项目（MRI）和化学研究仪器项目（CRIF）的支持下，来自马萨诸塞大学达特茅斯分校的David Manke教授及其同事Maolin Guo、Steven Haefner（桥水州立大学）、Sivappa Rasapalli和Jonathan Rochford（波士顿大学）将获得一台双源x射线衍射仪。一般来说，x射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于邻近分子的空间排列的准确信息。这里描述的研究将影响许多领域，包括有机和无机化学，材料化学和生物化学。该仪器不仅将成为马萨诸塞大学达特茅斯分校的教学、研究和研究培训的一个组成部分，而且还将成为马萨诸塞大学波士顿分校、桥水州立大学、罗德岛大学、萨尔维里贾纳大学、罗德岛学院和布朗大学等邻近机构的教学、研究和研究培训的一个组成部分。该奖项旨在加强各级的研究和教育，特别是在以下领域：(a)设计和合成路易斯碱衍生金属有机框架（mof），以选择性地从气体混合物中去除二氧化碳；(b)研究用于催化还原二氧化碳的盖顶混合双金属体系；(c)开发用于DNA位点特异性结合的单金属和双金属插入物；(d)研究用于光电、光催化二氧化碳还原和光声成像技术的分子系统；(e)研究铁和过氧化氢体内平衡的生物无机化学；(f)开发复杂有机分子的制备策略。

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor David Manke from the University of Massachussetts, Dartmouth and colleagues Maolin Guo, Steven Haefner (Bridgewater State University), Sivappa Rasapalli and Jonathan Rochford (U Mass Boston) will acquire a dual source X-ray diffractometer. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here will impact a number of areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research and research training not only at the University of Massachusetts Dartmouth but also at neighboring institutions such as the University of Massachusetts Boston, Bridgewater State University, University of Rhode Island, Salve Regina University, Rhode Island College, and Brown University which are part of a consortium.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) designing and synthesizing Lewis base derivatized metal-organic frameworks (MOFs) to selectively remove carbon dioxide from gaseous mixtures; (b) studying capped, mixed bimetallic systems for the catalytic reduction of carbon dioxide; (c) developing mono- and bi-metallo-intercalators for site specific binding of DNA; (d) investigating molecular systems for application in photovoltaics, photocatalytic carbon dioxide reduction and photoacoustic imaging technologies; (e) studying bioinorganic chemistry of iron and hydrogen peroxide homeostasis; and (f) developing strategies for the preparation of complex organic molecules.