CIF: Collaborative Research: Parallel Online Algorithms for Large-Scale MRI

这项工作提出了强大的模型，捕获了大动态磁共振成像（MRI）数据的特征，然后提供了架构和算法，同时揭示了对所涉及的各种分析和实现权衡的基本见解。所提出的框架将提取显著的全球趋势，以便对由于成像速度限制而缺失的MRI数据条目进行代入，并获得简洁的表示，以便从大量MRI数据池中处理和推断。利用低秩和稀疏感知信号处理、学习和优化、基于矩阵和张量模型的在线、并行和分散算法的进步，将能够使用并行处理器对序列测量进行流分析，并跟踪动态发展的数据集。该项目将直接影响高分辨率3D动态MRI技术，提高医疗诊断和治疗水平。开发的算法和工具将使技术转让惠及更广泛的人群并改善医疗保健。从该项目的大规模分析环境中获得的见解也将有利于大数据挖掘、神经科学、智能电网和健康信息学。拟议的研究与一项教育计划相结合，将进一步产生更广泛的影响，该计划旨在培养下一代医疗数据科学专业人才的新骨干，并促进学术研究与健康产业需求的相互促进。

This effort puts forth powerful models capturing the characteristics of big dynamic magnetic resonance imaging (MRI) data, and then offering architectures and algorithms, while revealing fundamental insights into various analytical and implementation trade-offs involved. The proposed framework will extract salient global trends to enable imputation for missing MRI data entries due to imaging speed limitations, and obtain parsimonious representations to process and draw inferences from big pools of MRI data. Leveraging advances in low-rank and sparsity-aware signal processing, learning and optimization, online, parallel, and decentralized algorithms based on matrix and tensor models, will enable streaming analytics of sequential measurements using parallel processors, and tracking dynamically evolving datasets. This project will directly impact high-resolution 3D dynamic MRI technology to improve medical diagnosis and treatment. The developed algorithms and tools will enable technology transfer to benefit a wide population and improve healthcare. Insights gained from this project's large-scale analytics context will also benefit big data mining, neuroscience, smart grid, and health informatics. Broader impact will be further effected by the integration of the proposed research with an educational plan designed to train the new cadre of next-generation of medical data science professionals, as well as promote cross-fertilization of academic research with health industry needs.