CAREER: Contact Charge Electrophoresis for Mobile Microfluidics

Bishop1351704最近发现的一种新型的电泳法，接触电荷电泳法(CCEP)很有趣，但本身并不是很有用，因为这种现象会导致带电粒子或液滴在两个电极之间振荡。PI绘制了一张路线图，说明如何通过使用棘轮来远距离移动颗粒并使用棘轮分离微流控设备中的颗粒，从而打破振荡并使运动线性化。他还计划使用新的模拟工具来理解CCEP的基本机制，并在他的实验室中验证他的模型。这种操纵小颗粒的新能力将对许多技术产生额外的影响，例如那些需要颗粒分离的技术，或者用于电子显示器、细胞分类和DNA测序的技术。

Bishop1351704The recent discovery of a new type of electrophoresis, contact-charge electrophoresis (CCEP), is interesting, but is not broadly useful per se in that the phenomenon results in a charged particle or droplet oscillating between two electrodes. The PI has drawn out a roadmap of how to break out of the oscillation and linearize the motion by using "ratchets" to move the particles through long distances and to use the ratchets to separate particles in microfluidic devices. He has also laid out plans to understand the basic mechanism of CCEP using new simulation tools and to validate his models in his laboratory. This new ability to manipulate small particles will have an additional impact on many technologies such as those that require particle separations or technologies used in electronic displays, cell sorting, and DNA sequencing.