Neurofeedback for Adult Attention-Defizit-/Hyperactivity Disorder (ADHD): A proof of principle comparison of Slow Cortical Potentials and Near-Infrared-Feedback with Placebo Treatment

注意力缺陷多动障碍(ADHD)的特征是注意力不集中、冲动和多动。到目前为止，只有几项研究对成人群体中的ADHD进行了研究，更少的研究对新的治疗形式进行了研究，如神经反馈训练。神经反馈训练在各个领域都得到了有效的应用，特别是在ADHD儿童的治疗中。本研究旨在研究慢皮质电位(SPC)神经反馈训练和一种新形式的神经反馈近红外光谱(NIRS)对成人ADHD患者症状和神经生理参数的影响。SCP和NIRS神经反馈治疗方法的比较以前从未进行过，可能会为成人ADHD的替代治疗提供有价值的结果。这两种神经反馈技术的结果将在30次训练课程和6个月的随访期后进行评估，并与安慰剂训练进行比较。此外，为了研究这项原则证明研究中的训练效果是否可以通过特定的神经生理学基线参数来预测，将使用回归模型。最后，将与健康对照组进行比较，以评估越轨训练前的神经生理学参数、评估措施的稳定性和治疗结果。

Attention deficit hyperactivity disorder (ADHD) is characterized by symptoms of inattention, impulsivity, and hyperactivity. Hitherto, only a few studies have investigated ADHD in an adult population and even less have investigated new forms of treatment such as neurofeedback training. Neurofeedback training has been applied effectively in various areas, especially in the treatment of children with ADHD. This study is designed to investigate the effect of slow cortical potentials (SPC) neurofeedback training and a new form of neurofeedback using near-infrared spectroscopy (NIRS) on symptomatology and neurophysiological parameters in an adult ADHD population.A comparison of SCP and NIRS neurofeedback therapy methods has not been previously conducted and may yield valuable findings about alternative treatments for adult ADHD. The outcome of both neurofeedback techniques will be assessed over 30 training sessions and after a six month follow-up period and compared to placebo training. Furthermore, to investigate if training effects in this proof of principle study can be predicted by specific neurophysiological baseline parameters, regression models will be applied. Finally, a comparison with healthy controls will be conducted to evaluate deviant pre-training neurophysiologic parameters, stability of assessment measures, and treatment outcome.