Genomics of Diseases in Wildlife Workshop; Colorado State University; June 3-9, 2018

该奖项为研究生提供资金，参加野生动物疾病基因组学研讨会。该讲习班是一次重要的培训和合作研究经验，重点是开发基因序列数据分析工具，以解决野生动物疾病生态学和进化问题。 这种经验通过围绕传染性野生动物疾病合作项目的实践练习，为学生和科学家提供实践培训。参与者学习的工具将使未来的研究能够利用日益增长的遗传数据。 该讲习班的目标是具有四个主要科学学科专门知识的早期和中期职业专业人员，以研究野生动物中宿主-病原体的相互作用：基因组科学;野生动物生物学;兽医科学;野生动物管理和保护。讲习班的组织者特别注重聚集一批不同的参与者，使其具有大致平等的性别平衡，并注意族裔和区域多样性。参与野生动物疾病基因组学的参与者将从头到尾使用下一代基因组序列数据来解决野生动物传染病的生态和进化问题。研讨会将讨论哪些序列数据适合于解决传染病生态学和进化领域的哪些问题。参与者将学习评估序列读取质量和覆盖率，将读取映射到参考基因组，执行宿主和病原体基因组的从头组装，并注释组装的基因组。从那里，他们将评估读取质量，为宿主和病原体内部和之间的比较分析创建比对。将包括几种形式的分析，重点是跨空间和时间的比较基因组学，包括与疾病爆发相关的演变模式。 所有这些活动将集中在最近可用的序列有关的野生动物疾病生态学的当前问题。这个奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。

The award provides funding for graduate students to participate in a Genomics of Diseases in Wildlife workshop. The workshop represents an important training and collaborative research experience focused on developing tools for the analysis of genetic sequence data to address problems in wildlife disease ecology and evolution. This experience provides hands on training to students and scientists through hands on exercises focused around a collaborative project in infectious wildlife disease. The tools participants learn will enable future research that capitalizes on the growing availability of genetic data. The workshop targets early and mid-career professionals with expertise in four major scientific disciplines to examine host-pathogen interactions in wildlife: genome sciences; wildlife biology; veterinary sciences; and wildlife management and conservation. Workshop organizers are focusing particular attention on assembling a diverse set of participants, with approximately equal gender balance, and attention to ethnic as well as regional diversity. Participants in this Genomics of Diseases in Wildlife will be taken from start to finish in the process of using next generation genomic sequence data to address questions in the ecology and evolution of infectious diseases of wildlife. The workshop will address which sequence data are appropriate to address what questions in the area of ecology and evolution of infectious disease. Participants will learn to assess sequence read quality and coverage, map reads to a reference genome, perform de novo assembly of host and pathogen genomes, and annotate assembled genomes. From there, they will assess read quality, create alignments for comparative analyses within and among hosts and pathogens. Several forms of analysis will be included with a focus on comparative genomics across space and time, including the patterns of evolution associated with disease outbreaks. All of these activities will focus on recently available sequence related to a current problem in wildlife disease ecology.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.