I-Corps: A Quantitative Approach to Detecting Meltdowns in Individuals with Autism Spectrum Disorder

这个I-Corps项目更广泛的影响/商业潜力将是改善自闭症谱系障碍（ASD）患者及其护理人员的生活质量。2014年，自闭症的患病率增加了15%。现在，在美国出生的59名儿童中就有1名患有ASD。这意味着美国大约有550万人不太可能上大学或在高中毕业后找到工作。我们的用户友好，谨慎的设备可以帮助受影响的个人获得独立，并为他们创造一个支持性的学习或工作环境。在当前市场上，实际上不存在先发制人的熔毁检测和护理设备。作为第一个以可承受的价格进入市场的公司，我们希望引领并催生衍生产品。除了自闭症，我们的平台技术还可以用于将数据推送给医疗保健专业人员，促进知情和个性化的预防护理。其他可想到的应用是监测顺应性和测量中风患者的肌肉接合的康复锻炼的有效性。我们的创新也有可能接触和帮助那些受其他类型焦虑症影响的人。它可以帮助人们更加了解自己的心理健康，进行干预，过上更健康的生活。这个I-Corps项目涉及可穿戴技术，用于预测，检测，跟踪和减轻自闭症谱系障碍（ASD）患者的崩溃。我们已经开发了一种生物识别传感套件，包括两个组件：硬件部分包括一个可拆卸的防水核心单元，用于生物信号过滤，处理和传输，以及可嵌入服装中的可机洗传感器;软件部分包括我们专有的机器学习模型，用于确定何时发生熔毁，警告父母或看护者熔毁的高风险，以及事后对缓解技术的评估。我们的创新将推进自闭症研究，因为该技术有可能为更好地理解行为表型打开大门。能够说出一个不会说话的孩子的感受，可以为社会/教育发展以及更广泛的表型研究提供更有效和富有成效的课程。我们产品的评估功能将导致熔毁缓解技术的改进。gaia的竞争优势在于其先发制人的性质。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this I-Corps project will be the improvement of the quality of lives of both the individuals with Autism Spectrum Disorder (ASD) and their caregivers. The prevalence of autism has increased by 15% in 2014. Now, 1 in 59 children born in the US has ASD. This translates to roughly 5.5 million individuals in the US who are less likely to go to college or find a job after high school. Our user-friendly, discreet device can help affected individuals gain independence and create a supportive learning or working environment for them. Pre-emptive meltdown detection and care devices are virtually non-existent in the current marketplace. As the first to enter the market at an affordable price point, we expect to lead and spawn derivative products. Beyond autism, our platform technology can be utilized to push data to a healthcare professional, catalyzing informed and personalized preventive care. Other conceivable application is monitoring compliance and measuring the effectiveness of rehabilitation exercises for muscle engagement of stroke patients. Our innovation also has the potential to reach and assist those affected by other types of anxiety disorders. It can help people become more informed about their own mental health, intervene, and lead healthier lives. This I-Corps project involves wearable technology for predicting, detecting, tracking, and mitigating meltdowns for individuals with Autism Spectrum Disorder (ASD). We have developed a biometric sensing suite comprising two components: The hardware portion consists of a detachable, water-resistant core unit for biosignal filtering, processing, and transmission as well as machine washable sensors that can be embedded into apparel; The software portion consists of our proprietary machine learning models for determination of when a meltdown is to occur, alerting the parent or caregiver of a high risk of a meltdown, and an assessment of mitigation techniques afterwards. Our innovation will advance autism research, as the technology has the potential to open the doors to a better understanding of behavioral phenotypes. Being able to tell what a non-verbal child is feeling can pave the way for more efficient and productive lessons for social/education development as well as broader phenotypical research. The assessment feature of our product will lead to the improvement of mitigation techniques for meltdowns. gaia's competitive advantage is in its pre-emptive nature of care. Proof-of-concept was demonstrated, and a beta prototype will be complete by the end of Summer 2018.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.