SBIR Phase II: User Application and Backend Portal to Enhance and Measure Addiction Treatment and Recovery Efficacy

这个小企业创新研究（SBIR）二期项目的更广泛的影响/商业潜力是进一步开发其队列招募工具的技术功能，这将推动推出一个生产质量的药物滥用障碍（SUD）研究平台，该平台专为大学、学术医疗中心和商业部门的成瘾研究人员设计，美国公共资助的成瘾研究每年超过14亿美元。该项目将使公司能够直接为更广泛的社会目标作出贡献，即减少药物滥用、成瘾和治疗服务对社会各阶层个人（如少数民族、退伍军人等）的负面影响和成本，使成瘾研究人员能够提出新的、更有效的成瘾康复支持和干预措施，这些支持和干预措施对提高健康结果和控制医疗保健成本至关重要。增强的功能将为SUD的研究人员和利益相关者提供一个独特的平台，以研究和利用现有证据来改进治疗方案、政策和融资，以改善成瘾康复的结果。开发该产品将使公司能够将其庞大的移动康复社区与最先进的研究工具相结合，为成瘾研究人员提供重要价值，并向公共和私人健康保险公司展示有效性。两个重要的目标客户。这项小企业创新研究（SBIR）第二阶段项目将帮助研究人员提出新的技术干预措施，并支持改善人口健康结果的科学方法。尽管技术正在兴起，以帮助解决康复支持问题，但这些技术尚未充分发挥其潜力，以满足努力保持清醒的人们的需求，包括SUD研究人员在内的从业者的需求，以及健康保险公司激励最佳实践并改善健康和控制成本的愿望。研究目标包括通过构建、测试和实施一个生产就绪的开源研究平台，扩展其对队列招募工具的概念验证，该平台具有进行科学研究的增强功能，包括参与者评估和干预计划、高级队列选择和前瞻性分配功能、自动化研究管理功能、白标比较应用程序、支持大型研究的高度可扩展架构。灵活的数据托管和管理功能，以及安全的软件更新基础设施。结果将是一个可扩展的、可伸缩的、开源的软件工具，用于进行各种科学严谨的行为研究，包括临床试验。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to further develop the technical functionality of its cohort recruitment tool that will advance efforts to launch a production quality substance abuse disorder (SUD) research platform designed for use by addiction researchers at universities, academic medical centers, and commercial sector where U.S. publicly-funded research on addictions exceeds $1.4 billion per year. The project will enable the company to contribute directly to broader societal goals of reducing the negative effects and costs of substance abuse, addiction, and treatment services to individuals from all sectors of society (e.g., minorities, veterans, etc.) by enabling addiction researchers to surface novel and more effective addiction recovery supports and interventions essential to enhancing health outcomes and controlling health care costs. The enhanced functionality will provide SUD researchers and stakeholders a unique platform to study and leverage existing evidence to improve treatment protocols, policies, and financing to improve addiction recovery outcomes. Developing the product will enable the company to combine its large mobile recovery community with state-of-the-art research tools that provide significant value to addiction researchers and demonstrate effectiveness to public and private health insurers ? two important target customers.This Small Business Innovation Research (SBIR) Phase II project will aid researchers in surfacing novel technical interventions and support scientific methods to improve population health outcomes. Although technologies are emerging to help address recovery support, these have not yet met their full potential for addressing the needs of people striving 24/7 to stay sober, the needs of practitioners including SUD researchers intent on supporting their recovery, and the desire for health insurers to incentivize best practices and to improve health and control costs. The research objectives include expanding on its proof-of-concept for a cohort recruitment tool by building, testing, and implementing a production-ready open-source research platform with enhanced features for conducting scientific studies including participant assessment and intervention scheduling, advanced cohort selection and prospective assignment features, automated study management features, a white label comparison app, highly scalable architecture enabling very large studies, flexible data hosting and management capabilities, and secure software update infrastructure. The result will be an extensible, scalable, and open-source software tool for conducting a broad variety of scientifically rigorous behavioral research studies, including clinical trials.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.