ACS Symposium on Antimicrobial and Cell-Penetrating Polymers

本次研讨会将为传播该领域的最新成果提供一个平台，并将作为一个广泛的跨学科论坛，讨论聚合物化学家、生物物理学家和微生物学家当前面临的挑战和机遇。关键贡献将描述化学结构，生物物理性质和合成聚合物的生物活性之间复杂的相互作用，这些聚合物被设计成模仿宿主防御肽的显着特征。优化聚合物结构以增强抗菌效力和降低对人体细胞的毒性将是一个重点关注的领域。此外，对这些合成大分子的作用机制的讨论将进一步促进它们在临床环境中的潜在未来应用。此次活动可能会引起聚合物科学与工程、生物物理学、微生物学和生物材料研究人员的浓厚兴趣。本次研讨会将有助于建立实验和计算研究人员之间的合作努力，以及弥合聚合物化学家和生物物理科学人员之间的差距。展示跨学科研究者的进步，同时培养下一代年轻科学家也是一个中心主题，因为它为新的研究途径提供了重点，并促进了下一代研究者的发展。重要的是加强在科学和工程领域代表性不足的群体的参与。确定的演讲者包括14名女科学家，3名少数民族和11名初级研究员（博士后研究员和助理教授）。研究生和博士后研究人员的演讲，包括代表性不足的群体的成员，将通过积极的广告和支持旅费的方式强烈鼓励。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This symposium will provide a platform for the dissemination of the current results in the field and will serve as a broad interdisciplinary forum for discussions on the current challenges and opportunities for polymer chemists, biophysicists, and microbiologists. The key contributions will delineate the complex interplay between chemical structure, biophysical properties, and biological activity of synthetic polymers that are designed to mimic the salient features of host defense peptides. Optimization of polymer structures to enhance antibacterial potency and reduce toxicity to human cells will be a key focus area. Additionally, discussions on the mechanisms of action exerted by these synthetic macromolecules will further facilitate their potential future use in a clinical setting. The event is likely to evoke keen interest to researchers who specialize in polymer science and engineering, biophysics, microbiology and biomaterials.This symposium will facilitate establishing collaborative efforts between experimental and computational researchers, as well as bridging the gap between polymer chemists and people in the biophysical sciences. Showcasing the advances of interdisciplinary investigators while training young scientists of the next generation is also a central theme as it provides focusing for new research avenues and fostering the development of the next generation of investigators. Significant are made to enhance the participation of groups underrepresented in science and engineering. The list of confirmed speakers includes 14 female scientists, 3 minorities, and 11 junior researchers (Postdoctoral Researchers and Assistant Professors). Presentations by graduate students and post-doctoral researchers, including members of underrepresented groups, will be strongly encouraged through active advertisement and support for travel expenses.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.