The 16th US-Korea Forum on Nanotechnology: Nanomedicine Focusing on Single Cell Level and Sensors Related to Human Cognition and Brain Research

从2003年开始，韩美两国之间的“纳米技术论坛”交替举行。论坛的重点是加强两国科学家和工程师在纳米技术转化领域的研究合作。具体来说，一个联合论坛促进了两国研究团体和机构之间的网络，使双方能够交换信息和探索研究合作的机会。今年的主题是聚焦于单细胞水平的纳米医学和与人类认知和大脑研究相关的传感器。此次论坛由8名美国资深演讲人和7名美国创业初期演讲人组成，韩国演讲人的人数也大致相同。本次论坛组委会力求强调多样性。本次论坛积极鼓励在纳米技术领域建立伙伴关系，以期在多个课题上取得突破，并加强以往论坛所取得的成就和评估以往论坛所提建议的进展。论坛的所有会议记录和调查结果都可以在卡内基梅隆大学的网站上找到。这个提议的论坛的贡献是它能够汇集一个两国专家研究人员和创新者的社区，他们致力于纳米医学的前沿，专注于单细胞水平和与人类认知相关的传感器。本次论坛将充分利用纳米技术与生物信息认知技术的融合，促进上述两个领域的发展。本次论坛的成果将导致两国具有里程碑意义的、充满活力的研究合作，纳米技术的融合将产生巨大的影响。随着我们进入第四次工业革命，其特征是技术融合，模糊了物理、数字和生物领域之间的界限，处理和存储的大量数据的快速增长导致我们需要一个新兴的技术领域，包括人类认知和纳米医学。为了充分探索这些技术，纳米技术与生物信息认知方法的融合将发挥关键作用。第十六届论坛将讨论以下两个议题：(a)聚焦于单细胞水平的纳米医学；纳米医学领域目前面临的挑战包括：(1)新开发材料的长期命运（空间和时间分布）以及如何将已开发的纳米材料协同应用；(2)纳米材料的利基；(3)改变医疗实践的一般范例；(4)精确监测患者的预防医学；(5)个性化医疗；(6)批次间一致性验证；(7)对更安全的生物材料的需求。viii)瞄准活动部件的能力。由于单细胞纳米医学的重要性，这一主题将在连续的论坛上进行讨论。(B)与人类认知和大脑研究相关的传感器：人类性能改变（HPM）的关键技术组件是纳米传感器。将研究具有新功能的新型纳米传感器，从而开创HPM时代。该技术包括图像处理单元和人工智能单元，仅举几例。通过增加感官输入和增强传感器，HPM最终可以极大地提高人类的日常表现。纳米技术的融合可能会导致新型传感器技术的发展，这些技术可以在HPM领域取得进展，包括视觉、听觉、味觉、嗅觉和体感。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Since 2003, the Forum on Nanotechnology Forum between U.S. and Korea has been held at alternating countries. The forum focuses on enhancing research collaboration in the field of nanotechnology conversion among scientists and engineers from both countries. Specifically, a joint forum facilitates networking between the research communities and agencies of both countries, enabling each side to exchange information and explore opportunities for research collaboration. This year the topics are nanomedicine focusing on single-cell level and sensors related to human cognition and brain research. The forum includes 8 senior presenters and 7 early-career presenters from U.S. and roughly equal number of Korean presenters will also participate. Organizing committee of this forum strives to place emphasis on diversity. This forum actively encourages partnerships in nanotechnology for breakthroughs in various topics, in addition to strengthening achievements and assessing the progress on recommendation made during the previous forums. All of the forum proceedings and findings are available on Carnegie Mellon's website for broad audiences. The contribution of this proposed forum is its ability to bring together a bi-national community of expert researchers and innovators who are working on the leading edge of nanomedicine focusing on single cell level and sensors related to human cognition. This forum will stimulate efforts to promote the above two areas by fully utilizing nanotechnology convergence to bio-information-cognitive technology. The outcome of this forum will lead to milestone and vigorous research collaboration of both countries where nanotechnology convergence will generate a great impact. As we enter the 4th industrial revolution, which is characterized by a fusion of technologies that is blurring the lines between the physical, digital, and biological spheres, the rapid increase in the enormous amount of data processed and stored led us to a need for an emerging field of technologies including human cognition and nanomedicine. To fully explore these technologies, nanotechnology convergence with bio-information-cognitive methods play a critical role. The following two topics will be scrutinized during this 16th Forum. (a) Nanomedicine focusing on single cell level: Current challenges in nanomedicine area involve i) long-term fate for newly developed materials (distribution in space and time) and how to integrate already-developed nano-materials into application synergistically, ii) the niche of nanomaterials, iii)changing the general paradigm of medical practice, iv) precisely monitoring patients for preventive medicine, v) personalized medicine, vi) batch-to-batch consistency validation, vii) need for safer biomaterial, and viii) ability to target moving parts. Due to the importance of single-cell nanomedicine, this topic will be examined during the consecutive forums. (B) Sensors related to human cognition and brain research: Key technical components of human performance modification (HPM) are the nanosensors. Novel nanosensors that are capable of new functions allowing an era in HPM will be investigated. This technology includes an image processing unit and an artificial intelligence unit to name a few. With added sensory inputs and augmented sensors, ultimately HPM can drastically enhance human performance on a daily basis. The convergence of nanotechnology is likely to result in the development of novel sensor technologies that can advance in HPM including vision, audition, gustation, olfaction, and somatosensation.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.