MRI: Acquisition of a laser scanning confocal microscope for cellular imaging for faculty and students at Baruch College

纽约市立大学巴鲁克学院获奖，以支持购买具有超分辨率能力的先进共焦显微镜系统。新系统将支持自然科学系教员当前和可预见的关键研究需求，包括固定和活样本的多色成像、时间推移成像、定量荧光、光激活、亚细胞结构和细胞器的可视化、生物发光生物的光谱分析、复杂组织的三维渲染和成像。该系统的多功能性使其能够适应现在和未来的各种实验方法，并将在未来几年最大限度地增加巴鲁克能够使用新设备的研究人员的数量。除了教师研究，作为个别指导研究和课堂教学的一部分，联合焦点还将用于培训研究生和本科生现代研究实践和技术。新的共聚焦成像系统将被自然科学系内至少九个研究小组及其合作者使用，他们的广泛和多学科的研究目标包括确定激素信号机制，阐明神经系统中活性氧物种的作用，鉴定海洋生物的生物发光，调查黑色素在真菌发病中的作用，确定肌肉附着部位的选择，阐明脊椎动物分化的基因调控途径，确定环境对昆虫行为的影响，以及物种形成的形态特征分类。这些数据将以同行评审出版物和在科学会议上发表的形式公布，并直接与感兴趣的研究人员和合作者分享。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to Baruch College, City University of New York to provide support for the acquisition of an advanced confocal microscopy system with super-resolution capacity. The new system will support the current and foreseeable critical research needs of the faculty in the Department of Natural Sciences, which include multi-color imaging of fixed and live samples, time-lapse imaging, quantitative fluorescence, photo-activation, visualization of subcellular structures and organelles, spectral analysis of bioluminescent organisms, 3-D rendering and imaging of complex tissues. The system's versatility makes it capable of accommodating a wide variety of experimental approaches now and in the future and will maximize the number of researchers at Baruch who can use the new equipment for years to come. In addition to faculty research, the confocal will also be used to train graduate and undergraduate students in modern research practices and technologies as part of individually mentored research and classroom instruction. The new confocal imaging system will be used by at least nine research groups within the Department of Natural Sciences and their collaborators, whose broad and multidisciplinary research objectives include the determination of hormone signaling mechanisms, elucidation of the role of reactive oxygen species in the nervous system, identification of bioluminescence in marine organisms, investigation of melanin in fungal pathogenesis, determination of muscle attachment site selection, elucidation of gene regulatory pathways governing vertebrate differentiation, identification of environmental impacts on insect behavior, and classification of morphological characteristics in speciation. These data will be publicized in the form of peer-reviewed publications and presentations at scientific meetings, as well as directly shared with interested researchers and collaborators.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.