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Functional Genomic Analysis of Exported DNAJ Molecules in the Malaria Parasite Plasmodium falciparum

Functional Genomic Analysis of Exported DNAJ Molecules in the Malaria Parasite Plasmodium falciparum
疟原虫恶性疟原虫输出 DNAJ 分子的功能基因组分析
批准号:
DP0878953
负责人:
Prof Dr Alexander Maier
金额:
$34.55万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2013-01-14

项目摘要

项目成果

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中文摘要
翻译
疟疾不仅是一个全球卫生问题,而且还影响到澳大利亚周边国家,如巴布亚新几内亚和印度尼西亚,降低了该地区的稳定和繁荣。环境变化和人们流动性的增加(例如,援助和安全人员)使澳大利亚本身更容易感染疟疾。该项目将利用前沿技术将最新的基因组数据转化为功能洞察力,以确定恶性疟原虫感染的新干预目标。开发新的靶标是人类的使命,也是为了保护澳大利亚地区免受这种疾病的社会和经济影响。澳大利亚开发的干预措施将提高其科学在全球的能见度,导致投资增加。
英文摘要
Malaria is not only a global health problem, but also affects countries surrounding Australia like PNG and Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (eg. aid and security personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identify new intervention targets for P. falciparum infection. Developing novel targets is mandated by humanity, and also to safeguard Australia's region against the social and economical implication of this disease. An Australian developed intervention would increase the global visibility of its science, leading to increased investments.
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Targeting the host lipid environment to disrupt malaria transmission
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Signalling pathways for sexual differentiation of apicomplexan parasites
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  • 项目类别:
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Biogenesis of red blood cell membrane modifications by the malaria parasite Plasmodium falciparum
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  • 项目类别:
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  • 财政年份:
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  • 负责人:
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  • 依托单位:
海外基金