PFI (RAPID): COVID Rapid Response Innovation Community

这一创新伙伴关系快速项目的更广泛影响/商业潜力是使创新技术解决方案能够高效有效地转化，以满足与新冠肺炎相关的一线医疗短缺。大流行引发了严重的供应链短缺。非医疗工程师提供设计和原型解决方案，但他们的专业知识和创新无法有效地发挥作用。这些工程创新者缺乏与一线医疗决策者的联系，也不熟悉与医疗设备交付相关的严格要求和流程。在大流行期间填补紧急短缺表明，需要迅速确保安全，同时也考虑快速规范、设计、扩展、测试和部署。因此，该PFI快速项目旨在开发、部署和评估互联快速创新系统，以满足解决方案(危机系统)确定的需求，从而满足宾夕法尼亚州费城的供应链短缺。危机系统将简化设备开发/交付流程，并在创新工程师和当地医疗决策者之间建立有效、持续的联系-所有这些都旨在提供技术创新，以解决一线短缺问题。弗拉拉·温斯顿博士和她的团队将把妇女和少数族裔作为努力的一部分，并将让公众参与到科学和技术中来。该项目可能会通过解决与新冠肺炎相关的一线医疗器械短缺问题产生立竿见影的效果，并成为一个强大的、现实世界的测试案例，未来将扩展到针对未来灾难和紧急短缺的互联、高效的响应。为了建立、部署和评估危机系统，该小组提出了两个目标。在目标1中，工作组建议建立互联系统和相关流程，以纳入医疗器械开发的最佳实践，并实现有效、有目的的系统创新。在目标2中，他们将通过应用新的人工智能方法建立匹配的后端(在设备/产品需求与技术专门知识和资源之间)，以便利用多种数据来源(从公共数据到私人公司数据)以及对匹配程度的实时估计。温斯顿博士和她的团队将使用持续质量改进的方法，从每个创新周期中学习如何优化过程和匹配。最终目标将是为新冠肺炎高效提供技术解决方案。如果新冠肺炎在当地层面被证明是成功的，那么吸取的经验教训、创新库和软件将可用于大规模创新，释放在其他灾难期间满足需求的潜力。该奖项反映了美国国家科学基金会的法定使命，并已通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this Partnerships for Innovation (PFI) RAPID project is to enable the efficient and effective translation of innovative technology solutions to meet frontline medical shortages related to COVID-19. The pandemic triggered critical supply chain shortages. Non-medical engineers offered design and prototype solutions, but their expertise and innovations could not be deployed efficiently. These engineering innovators lacked connections to frontline healthcare decision-makers and were unfamiliar with the rigorous requirements of and processes related to the delivery of healthcare devices. Filling urgent shortfalls during a pandemic exemplifies the need to quickly assure safety while also considering rapid specification, design, scaling, testing and deployment. Therefore, this PFI RAPID project aims to develop, deploy, and evaluate the Connected Rapid Innovation System to meet Identified needs with Solutions (the CRISIS System) in order to satisfy supply chain shortages in Philadelphia, PA. The CRISIS system will streamline device development/delivery processes and create impactful, sustained connections between innovative engineers and local healthcare decision-makers – all with the goal to deliver technological innovations to solve frontline shortages. Dr. Flaura Winston and her team will include women and minorities as part of the effort and will engage the public in science and technology. This project may have an immediate benefit by addressing frontline medical device shortages related to COVID-19 and serve as a robust, real-world test case for future expansion to connected, efficient responses for future disaster and emergency shortages. In order to build, deploy and evaluate the CRISIS System, the team proposes two aims. In Aim 1, the group proposes to build the connected system and associated processes to incorporate best practices in medical device development and enable efficient, purposeful, systematic innovation. In Aim 2, they will build the back-end for matchmaking (between device/product needs and technical expertise and resources) through the application of novel artificial intelligence methods in order to employ multiple data sources (from public data to private corporate data) as well as real-time estimations of the degree of matching. Dr. Winston and her team will use continuous quality improvement methods to learn from each innovation cycle about how to optimize both the processes as well as the matches. The ultimate goal will be efficient delivery of technological solutions for COVID-19. If proven successful on the local level for COVID-19, the lessons learned, library of innovations, and software will be available for mass scale-up of innovation, unlocking the potential to meet needs during other disasters.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.