MRI: Acquisition of an EEG for Examination of Brain-Behavior Relationships Across the Lifespan

这一重大研究仪器奖支持收购脑电(EEG)系统(ANT Neuro eego Mylab128通道)，以在东密歇根大学(EMU)建立第一个用于脑成像的EEG实验室。EEG是一种非侵入性的人脑成像方法，它以毫秒级的精度测量人类大脑中因思维和行为而产生的神经电活动。EEG实验室关键地扩展了心理学、传播学和障碍学系以及跨学科神经科学项目(心理学、生物学、化学)的神经科学培训和研究。脑电实验室对机构社区也有重大的地区性影响。EMU被公认为中西部最多元化的大学之一。EEG实验室使动车组能够为科学界的更广泛目标做出贡献，以招募、保留和提拔矿化团体的成员进入STEM领域。该实验室允许举办研讨会，对当地和地区的教职员工和学生进行神经成像方面的培训，作为发展研究助学金和奖学金的催化剂，面向未被充分代表的学生，包括来自农村社区的学生，并在与麦克奈尔学者计划为对脑电研究感兴趣的学生创建指导伙伴关系方面发挥核心作用。EEG实验室加强了与区域机构合作的EMU内的合作研究工作，并促进了在发展神经科学方面的国家合作。婴儿/儿童和老年人基本认知和行为过程(例如注意力和语言)的大脑机制的知识，发育变化的准确时间，以及影响这一时间的关键环境因素的知识，一直落后于年轻人的研究，仍然是研究的前沿。EEG是非侵入性的，婴儿和儿童耐受性很好。该研究小组检查了脑电信号以及关键认知和行为过程的发育时间，包括注意力和工作记忆、运动控制、自我调节、睡眠和交流。探讨了脑电事件相关电位、频率(功率)和大脑连通性在发展神经网络中的作用。为了阐明注意和社会交流之间的关系，我们研究了婴儿期/幼儿时期支持默认模式和背部注意网络和定向系统发展的电生理机制(频谱功率和连接性)。双手和单手运动控制随寿命的变化的神经相关性以及不一致的手偏好和手优势的神经基础正在被研究。研究人员正在研究事件相关电位的发育变化和环境前体，这些电位被假设为自我调节的基础。对儿童早期午睡功能的研究，包括神经生理学和行为，提供了关于睡眠-觉醒调节发展和注意力发展之间的相互关系的重要信息。最后，很少有研究研究老年人工作记忆--语言过程背后的神经生理机制。该奖项反映了NSF的法定使命，通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

This Major Research Instrumentation award supports the acquisition of an Electroencephalography (EEG) system (ANT Neuro eego mylab128-channel) to establish the first EEG laboratory for brain imaging at Eastern Michigan University (EMU). EEG is a non-invasive human brain imaging method that measures neural electrical activity in the human brain arising from thinking and behavior with millisecond accuracy. The EEG laboratory critically expands neuroscience training and research in the Departments of Psychology, Communication Sciences and Disorders, and the interdisciplinary Neuroscience Program (Psychology, Biology, Chemistry). The EEG laboratory also has a substantial regional impact on the institutional community. EMU is recognized as one of the most diverse universities in the Midwest. The EEG laboratory allows EMU to contribute to the broader aims of the scientific community to recruit, retain, and promote members of minoritized groups into STEM fields. The laboratory allows for workshops to train local and regional faculty and students on neuroimaging, serve as a catalyst for the development of research assistantships and fellowships targeted for underrepresented students, including those from rural communities, and be central in creating a mentoring partnership with the McNair Scholars Program for students interested in EEG research. The EEG laboratory enhances collaborative research efforts within EMU, with partnering regional institutions, and foster national collaborations in developmental neuroscience.Knowledge of the brain mechanisms underlying fundamental cognitive and behavioral processes (e.g. attention and language) in infants/children and older adults, the precise timing of developmental changes, and knowledge of crucial environmental factors that impact this timing has lagged behind research with younger adults and remains a frontier of investigation. EEG is non-invasive and well-tolerated by infants and children. This team examines the EEG signals and developmental timing of key cognitive and behavioral processes including attention and working memory, motor control, self-regulation, sleep, and communication. EEG event-related potentials, frequency (power), and brain connectivity in developing neural networks are explored. The electrophysiological mechanisms (spectral power and connectivity) underpinning the development of the default mode and dorsal attention networks and orienting system in infancy/toddlerhood are examined to clarify the relationships between attention and social-communication. The neural correlates of change of bimanual and unimanual motor control across the lifespan as well as the neural underpinnings of inconsistent hand preference and hand dominance are being investigated. Investigators are examining developmental changes and environmental precursors of event-related potentials hypothesized to underlie self-regulation. Investigation of the functions of napping, including neurophysiology and behavior, in early childhood provide vital information on reciprocal relations between the development of sleep-wake regulation and the development of attention. Finally, few studies have examined the neurophysiological mechanisms underlying working memory-linguistic processes in older adults. EEG is being used to explore the long-term learning effects and the compensatory processes that occur in older adults.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.