MRI: Acquisition of Active Holders for in-situ and in-operando Transmission Electron Microscope Experiments

该主要研究仪器（MRI）奖支持为密苏里大学基于用户的原位透射电子显微镜（TEM）测试设施购买先进仪器。该仪器将在成像时对各种样品进行动态测试。这包括一个带有残余气体分析仪的气相测试池，一个具有电化学能力的液相测试池，以及一个具有加热和偏置能力的真空测试池。为了消除传统上扼杀原位TEM实验的不良图像漂移，该仪器还将提供主动图像稳定。该仪器套件将安装在密苏里大学电子显微镜中心，并将供教育和工业用户使用。这套仪器在生物和材料研究中有多种应用。示例活动包括以下项目：Pt电催化剂和碳纳米管催化剂系统的活性将使用Protochips Atmosphere系统在高温下以原子分辨率进行检测。机载残余气体分析仪将提供催化剂颗粒激活和灭活时气体成分变化的定量测量。胶体纳米粒子和生物分子的自组装将由Protochips Poseidon Select实现。通过Protochips轴突同步系统，可以对单个粒子进行精确的三维跟踪。在电流作用下，将使用Fusion Select系统检测阴极/固体电解质连接处的界面材料在操作中形成。所有实验都将受益于由Protochips轴突同步提供的动态硬件和软件支持的稳定。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This Major Research Instrumentation (MRI) award supports the acquisition of advanced instrumentation for a user-based in-situ Transmission Electron Microscopy (TEM) testing facility at the University of Missouri. The instrumentation will enable dynamic testing of diverse samples while imaging. This includes a gas-phase test cell with residual gas analyzer, a liquid-phase test cell with electrochemical capabilities, and a vacuum cell with heating and biasing capabilities. To eliminate the undesirable image drift that traditionally stifles in-situ TEM experiments, the instrument will also provide active image stabilization. The instrument suite will be installed in the University of Missouri Electron Microscopy Center and will be accessible for educational and industrial users.The suite of instrumentation has diverse application in biological and materials-based research. Example activities include the following projects: The activity of Pt electrocatalysts and carbon nanotube catalyst systems will be examined with atomic resolution at elevated temperatures using the Protochips Atmosphere system. The on-board residual gas analyzer will provide a quantitative measurement of gas composition change as catalyst particles activate and de-activate. The self-assembly of colloidal nanoparticles and biomolecules will be enabled by the Protochips Poseidon Select. Precise three-dimensional tracking of individual particles is enabled by the Protochips Axon Synchronicity system. The in-operando formation of interphase materials at cathode/solid electrolyte junctions under electrical current will be examined using the Fusion Select system. All experiments will benefit from the dynamic hardware and software-enabled stabilization provided by the Protochips Axon Synchronicity.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.