Conference: Society for Research on Biological Rhythms: From Molecules to Policy

几乎所有的生物体都进化出了分子、细胞、生理和行为上的适应性，以预测环境中的规则振荡。因此，生物节律是地球上生命的核心组成部分，从秒级的振荡到季节尺度的振荡。在过去的世纪里，对生物节律的研究发现了一个精致的细胞和分子计时系统，它影响着从生理到行为的一切。事实上，在2017年，我们领域的一群先驱因其突破性的工作而被授予诺贝尔生理学或医学奖。虽然生物钟是生命的一个基本方面，但它们对广泛的生物过程的影响最终得到了重视。我们对生物节律如何影响生命科学的许多领域的理解越来越多，开始为我们如何看待公共卫生，劳动和教育系统以及建筑环境的后果提供信息。生物节律研究学会（SRBR）2022年会议的目标是促进从“分子到政策”的讨论，并突出高级和初级科学家的开创性工作。这项活动包括扩大SRBR努力建立的指导和培训工作。重点是从代表性不足的少数民族人口中招募和保留成员，并增加我们社区的多样性。生物计时专家与其他科学家、工程师和政策制定者之间的合作对于提高人们对生物节律的全球影响的认识至关重要。2022年SRBR会议的主题“从分子到政策”将直接迎接这一挑战。比较方法是这次会议的一个关键组成部分，包括模式和非模式生物，以及对微生物、植物、人类和非人类动物的实验室和实地研究。该计划的主题包括计时的神经网络，细菌和微生物的节奏，振荡系统的数学模型，“大数据”中节奏的分析策略，时间治疗学，节奏对新陈代谢的影响，甚至生物节律和COVID-19大流行的交叉点。科学计划具有包容性，多样性和及时性。SRBR 2022促进并努力维持一个多元化和包容性的科学界。该提案的一个关键组成部分是支持为期一天的培训生和专业发展活动，其中包括针对培训生和初级教师的数十个正式讲习班和培训活动。除了会议期间的正式和非正式辅导和培训活动外，这一为期一天的活动为学员积极参与会议奠定了基础。SRBR 2022通过各种奖项和奖学金促进来自低收入国家的代表性不足的群体和研究人员的参与，以提高参与率和提高保留率。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Nearly all organisms have evolved molecular, cellular, physiological and behavioral adaptations to predict regular oscillations in the environment. As such, biological rhythms are a core component on life on Earth, and run the gamut from oscillations occurring on the scale of seconds, and those on the scale of the seasons. The study of biological rhythms over the past century has led to the discovery of an exquisite cellular and molecular timekeeping system, which impacts everything from physiology to behavior. Indeed, in 2017 a group of pioneers in our field were awarded the Nobel Prize for Physiology or Medicine for their groundbreaking work unravelling this molecular puzzle. While biological clocks are a fundamental aspect of life, their effects on a wide range of biological processes are finally being appreciated. Our growing understanding of how biological rhythms impact many areas of the life sciences is starting to inform how we think about public health, labor and education systems, and the consequences of the built environment. The objective of the Society for Research on Biological Rhythms (SRBR) 2022 meeting is to foster discussion from “molecule to policy”, and highlight the groundbreaking work of both senior and junior scientists. The activity includes expansion of the mentoring and training efforts that SRBR has worked hard to establish. Emphasis is placed on recruitment and retention of members from underrepresented minority populations and increasing the diversity of our community. Collaboration between experts in biological timing and other scientists, engineers, and policy makers is critical to increase awareness of the global impact of biological rhythms. The theme for the 2022 SRBR meeting, “From Molecule to Policy”, will directly embrace this challenge. Comparative approaches are a critical component of this meeting, with inclusion of both model and non-model organisms, as well as both laboratory and field studies, in microbes, plants, humans and in non-human animals. The program includes topics such as the neural networks of timekeeping, rhythms in bacteria and microbes, mathematical models of oscillatory systems, analysis strategies for rhythms in “Big Data”, chronotherapeutics, effects of rhythms on metabolism, and even the intersection of biological rhythms and the COVID-19 pandemic. The scientific program is inclusive, diverse, and timely. SRBR 2022 fosters and strives to maintain a diverse and inclusive scientific community. A key component of this proposal is the support of the day-long Trainee and Professional Development event, which includes dozens of formal workshops and training events targeted at trainees and junior faculty. In addition to formal and informal mentoring and training events during the conference, this day-long event sets the stage for trainees’ active participation in the meeting. SRBR 2022 promotes increased attendance of underrepresented groups and researchers from low-income countries through a variety of awards and fellowships, with the goal of increasing participation as well as improving retention.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.