REU Site: Comparative Animal Model Approaches to Regeneration and Aging

这个REU网站奖给山沙漠岛生物实验室（MDIBL），位于巴尔港，ME，将支持10名学生的培训10周在2023年至2025年的夏天。预计共有30名学生，主要来自研究机会有限的学校或代表性不足的群体，将在该方案中接受培训。学生将在他们的本科学习的各个阶段，并将给予特别考虑有兴趣在显微镜和比较动物模型研究再生和老化的申请人。学生将学习如何进行研究，许多人将在科学会议上展示他们的工作成果。该计划的评估将通过在线SALG URSSA工具进行。学生将被要求在NSF ETAP系统（etap.nsf.gov）注册，并在程序后跟踪，以确定他们的职业道路。这个REU程序MDIBL将让学生接触比较动物模型方法，用于了解再生和衰老的生物学。该REU网站的实验室对细胞，组织，器官和肢体在受伤后或正常发育过程中如何修复或补充以及保留或重新使用以确保生物体在发育完成后蓬勃发展的机制感兴趣。为了回答这些问题，MDIBL的研究人员使用了各种动物模型。这些动物包括斑马鱼、鳉鱼、蝾螈、果蝇（果蝇）和线虫（秀丽隐杆线虫），它们可用于比较物种间衰老和再生策略的遗传相似性和差异。学生将通过专题讨论会，研讨会，活动，负责任的研究培训和每周的职业讨论，充分融入MDIBL的科学文化。有关该计划的更多信息，请访问NSF ETAP注册系统和https：//mdibl.org/education/student-fellowships/reu-summer-fellowships/，或联系PI（Updike博士，dupdike@mdibl.org）或co-PI（迪士尼博士，jdisney@mdibl.org）。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

This REU Site award to the Mount Desert Island Biological Laboratory (MDIBL), located in Bar Harbor, ME, will support the training of 10 students for 10 weeks during the summers of 2023-2025. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities or from underrepresented groups, will be trained in the program. Students will be at all stages of their undergraduate studies, and special consideration will be given to applicants interested in microscopy and comparative animal model research on regeneration and aging. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. Assessment of the program will be done through the online SALG URSSA tool. Students will be required to register in the NSF ETAP system (etap.nsf.gov) and tracked after the program to determine their career paths.This REU program MDIBL will expose students to comparative animal model approaches used to understand the biology of regeneration and aging. Labs at this REU site are interested in how cells, tissues, organs, and limbs are repaired or replenished after injury or during the ordinary course of development and the mechanisms retained or reemployed to ensure an organism thrives once development is complete. To answer these questions, researchers at MDIBL use various animal models. These animals include zebrafish, killifish, axolotl, fruit flies (Drosophila), and nematodes (Caenorhabditis elegans), which can be used to compare the genetic similarities and differences in aging and regeneration strategies across species. Students will be fully integrated into the scientific culture of MDIBL through symposia, seminars, activities, responsible conduct of research training, and weekly career discussions. Students More information about the program is available in the NSF ETAP registration system and by visiting https://mdibl.org/education/student-fellowships/reu-summer-fellowships/, or by contacting the PI (Dr. Updike at dupdike@mdibl.org) or the co-PI (Dr. Disney at jdisney@mdibl.org).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.