Coordination Funds

我们打算将TP Z中的活动安排为：(A)协调研究单位使用的动物模型，以提高可比性；(B)提高公众对肌肉骨骼再生在衰老、免疫适应性和机械适应性方面的认识；(C)利用柏林-勃兰登堡临床科学家再生疗法学校(GEROK)的基础设施，构建教育结构；以及(D)继续开展拟议研究单位参与者在其以前的工作中开展的国际科学联网活动，以强调调查老龄化对再生的影响的重要性。要在人类患者身上验证小鼠模型的研究结果，获得合格的人类血肿是至关重要的。因此，一个特殊的特点是可以从特定年龄段的骨折患者身上获取人体血肿。采集将在BCRT核心单元细胞采集的帮助下进行协调。所有血肿都将准备好进行分析、储存并提供给不同的小组，以便向他们提供与研究股内血肿和小鼠模型组织中的发现相关的人类样本数据。

We intend to structure the activities in the TP Z towards: (a) coordinating the animal models used in the Research Unit to enable better comparability; (b) raising public awareness of musculoskeletal regeneration with respect to aging, immunological fitness and mechanical adaptability; (c) structuring of education by using the infrastructure of the Berlin-Brandenburg School for Regenerative Therapies specifically for clinical scientists (GEROK), and (d) continuation of the international scientific networking activities that have been developed among the participants of the proposed Research Unit during their previous work in order to emphasize the importance of investigating the influence of aging on regeneration. To validate findings from mouse models in human patients, access to qualified human hematomas is essential. Thus a special feature will be the access to harvested human hematoma from fracture patients within specified age groups. The harvesting will be coordinated with the help of the BCRT core unit ¿cell harvest¿. All hematomas will be prepared for analysis, stored and made available for the different groups to provide them with human sample data that serve as correlate to findings in hematoma and tissue of the mouse models within the Research Unit.