Nanostructured Surfaces from Planet-Satellite Assemblies of Nanoparticles

在本项目中，将研究由RAFT聚合的星形聚合物连接在一起的两种纳米颗粒制成的行星-卫星结构，并对其尺寸和粒子排列进行优化。它将被研究，星型聚合物的哪个臂，它们中有多少连接着粒子，这些连接有多强。通过使用纳米颗粒和星形聚合物的变化以及纳米颗粒的功能化，我们将解决和研究这些自组装结构的不同功能（例如，传感或电荷分离）。此外，我们还将研究纳米纤维或纳米棒是否可以作为被第二种纳米粒子包围的中心粒子。最后，将行星-卫星结构附着在表面并稳定，以获得新的纳米结构表面。两种类型的粒子的功能化导致表面，两种类型的功能在纳米尺度上有规律地交替。我们将把肽配体固定在这些结构表面上，这将用于细胞和肿瘤迁移研究。对于这些研究，精确控制配体密度和功能模式是必不可少的。

In this project, planet-satellite structures made from two types of nanoparticles, which are linked together by star polymers from RAFT polymerization, will be investigated regarding their detailed structure, and their dimensions and particle arrangements will be optimized. It will be studied, which arms of the star polymers and how many of them are linking the particles and how strong these linkages are. By variation of the used nanoparticles and star polymers as well as by functionalization of the employed nanoparticles, we will address and investigate different functions (e.g., sensing or charge separation) to these self-assembling structures. I will additionally be studied, whether nanofibres or nanorods may act as the central particle that is surrounded by the second type of nanoparticle. Finally, the planet-satellite structures will be attached to surfaces and stabilized in order to obtain new nanostructured surfaces. Functionalization of the two types of particles leads thus to surfaces, on which two types of functions alternate regularly on the nanometer-scale. We will fix peptide-ligands to these structured surfaces, which will be used for cell- and tumor-migration studies. For these investigations, a precise control of ligand density and function pattern is essential.