Proteomanalytik und Massenspektrometrie (B16*)

这个项目的目的是表征决策背后的感觉皮层值计算。通过结合多通道记录在行为动物和MEG记录在人类中，我们将调查的时间动态的值表示在神经元振荡的水平上的局限的本地电路和大规模的活动分布在整个新皮层。药理学操作将用于测试这些值表示的动态基础的候选机制。最后，通过将类似的计算模型应用于啮齿动物和人类数据集，我们将能够描述自适应值表示和选择的共同功能原理。

This project aims at characterising sensory cortical value computations underlying decision making. By combining multichannel recordings in behaving animals and MEG recordings in humans we will investigate the temporal dynamics of value representations in neuronal oscillations both at the level of circumscribed local circuits and larger-scale patterns of activity distributed across the entire neocortex. Pharmacological manipulations will be used to test candidate mechanisms underlying the dynamics of these value representations. Finally, by applying similar computational models to both the rodent and human data sets we will be able to describe common functional principles of adaptive value representations and choice.