Influence of an oral health optimised diet on the subgingival biofilm

在一项初步研究中，四周的饮食变化，包括减少碳水化合物和丰富的欧米茄-3-脂肪酸，维生素C，D和纤维，已经能够显着降低牙龈和牙周炎症参数。因此，提案中所述研究的目的是在一项前瞻性、随机和对照研究中调查相同饮食变化对龈下生物膜的影响。在饮食改变之前和之后采集的15名参与者的龈下菌斑样本将用焦磷酸测序进行分析，并与15名未改变饮食的参与者的对照样本进行比较。此外，将对临床和血清学参数的结果进行分析。该申请是在“2. Nachwuchsakademie Zahnmedizin”.

In a preliminary study, a four-week dietary change including reduction of carbohydrates and enrichment of Omega-3-fatty acids, Vitamin C, D and fibers, has been able to significantly reduce gingival and periodontal inflammatory parameters. Therefore, the aim of the study described in the proposal is to investigate the influence of the same dietary change on the subgingival biofilm in a prospective, randomised and controlled study. Subgingival plaque samples of 15 participants, taken before and after the dietary change will be analysed with pyrosequencing and compared to control samples of 15 participants who did not change their diet. Furthermore, results are going to be analysed regarding clinical and serological parameters. The application is made within the framework of the "2. Nachwuchsakademie Zahnmedizin".