Evolution and the immune system: genetic differences in immune response between human populations due to adaptation to living in different geo-climatic locations

该项目研究人群间免疫反应差异的遗传学，将推动免疫学和人群遗传学研究的进步，解释目前人群特定疾病发病率的差异，并可能预测哮喘和过敏等疾病的未来人群趋势。这项研究将加强与世界各地的合作者的联系，从而促进澳大利亚研究的卓越，并在国际社会中赢得澳大利亚作为一个产生具有全球意义的研究的国家的声誉。了解免疫系统“最近的进化根源”对澳大利亚人的健康具有重要意义，特别是考虑到澳大利亚的种族背景日益多元化。

The project, which investigates the genetics of inter-population differences in immune response, will lead to advances in immunology and population genetics research, explain present population specific differences in disease incidence and possibly forecast future population trends of diseases such as asthma and allergy. The study will strengthen ties with collaborators around the world, thus promoting excellence in Australian research and gain Australia prestige in the international community as a country that produces research of global significance. Understanding the immune system's 'recent evolutionary roots' has implications for the health of Australians, especially in light of Australia's increasingly multi-ethnic background.