Functional analysis of the autophagy specific to filamentous fungi

自噬的分子生物学已经开始使用酿酒酵母，它在真核生物中的重要作用不仅在酵母中被发现，在哺乳动物细胞中也被发现。然而，人们对丝状真菌知之甚少。丝状真菌，如曲霉，米曲霉随着环境的变化而分化成分生孢子。从米曲霉中分离并鉴定了许多与自噬相关的基因。分析了丝状真菌特有的自噬的功能和作用。

Molecular biology of autophagy has started using yeast S. cerevisiae, and its important roles in eukaryotes have been revealed in not only yeast but also mammalian cells. However, little is known about filamentous fungi. Filamentous fungi such a Koji mold, Aspsergillus oryzae differentiates into conidia formation upon environmental change. Many autophagy-related genes from A. oryzae were isolated and characterized. Function and roles of autophagy specific to filamentous fungi have been analyzed.