Interaction of non-Newtonian fluids with deformable structures in microscale biological processes

在2022财年，我们开发了工具，为进行关键的硅内实验奠定了基础。最初，我们开发了该算法，并在内部并行有限元代码中实现了它。我们对通过单个可变形柱体的VFSI进行了严格的网格和时间步细化收敛测试。我们发现，该方法在空间和时间上表现出二阶精度。我们还用粘弹性流动的微流体实验对数值结果进行了验证，得到了半定量的结果。所有的结果都汇总在一份手稿中，这份手稿将发表在《应用力学和工程中的计算机方法》杂志上。

In FY2022, we developed the tools and laid the foundations for making the key in-silico experiments. Initially, we developed the algorithm and implemented it in the in-house parallel FE code. We performed strict mesh and time-step refinement convergence tests for VFSI past a single deformable cylinder. We found that the method exhibits second-order accuracy in space and time. We also validated the numerical results with microfluidic experiments of viscoelastic flow past two cantilevered cylinders; semi-quantitative agreement was achieved. All the results are summarized in a manuscript that will be submitted in the journal "Computer Methods in Applied Mechanics and Engineering".